vha-18 putative V-type proton ATPase subunit H 1 [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: vha-18
Official Full Name: putative V-type proton ATPase subunit H 1
Primary source: WormBase:WBGene00018698
Locus tag: CELE_F52E1.10
See related: AllianceGenome:WB:WBGene00018698
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable proton-transporting ATPase activity, rotational mechanism. Predicted to be involved in proton transmembrane transport. Predicted to be part of vacuolar proton-transporting V-type ATPase, V1 domain. Orthologous to human ATP6V1H (ATPase H+ transporting V1 subunit H). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See vha-18 in Genome Data Viewer

Location:: chromosome: V

Exon count:: 6

Sequence:: Chromosome: V; NC_003283.11 (8411775..8413482, complement)

Chromosome V - NC_003283.11 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

F52E1.10 (e-PCR)
- UniSTS:312341

F52E1.1 (e-PCR)
- UniSTS:306384

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables proton-transporting ATPase activity, rotational mechanism	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in proton transmembrane transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
part_of vacuolar proton-transporting V-type ATPase, V1 domain	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: putative V-type proton ATPase subunit H 1

NP_505171.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

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Reference assembly

Genomic

NC_003283.11 Reference assembly

Range

8411775..8413482 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_072770.7 → NP_505171.1 putative V-type proton ATPase subunit H 1 [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_505171.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q20666

Conserved Domains (1) summary

cd00256
Location:12 → 445

VATPase_H; VATPase_H, regulatory vacuolar ATP synthase subunit H (Vma13p); activation component of the peripheral V1 complex of V-ATPase, a heteromultimeric enzyme which uses ATP to actively transport protons into organelles and extracellular compartments. The ...