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    cest-2.1 Carboxylesterase type B domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 179916, updated on 9-Dec-2024

    Summary

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    Official Symbol
    cest-2.1
    Official Full Name
    Carboxylesterase type B domain-containing protein
    Primary source
    WormBase:WBGene00013875
    Locus tag
    CELE_ZC376.3
    See related
    AllianceGenome:WB:WBGene00013875
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be located in membrane. Human ortholog(s) of this gene implicated in colorectal cancer and gastrointestinal system cancer. Orthologous to human CES1 (carboxylesterase 1) and CES4A (carboxylesterase 4A). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See cest-2.1 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    11
    Sequence:
    Chromosome: V; NC_003283.11 (14168360..14171481, complement)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Carboxylic ester hydrolase Neighboring gene ONECUT (homeobox) Associated Motif containing Neighboring gene Carboxylesterase type B domain-containing protein Neighboring gene Carboxylesterase type B domain-containing protein Neighboring gene Homeobox domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. C30F12.4 influences oogenesis, fat metabolism, and lifespan in C. elegans. Wang L, et al. Protein Cell, 2016 Oct. PMID 27638466, Free PMC Article
    2. Distinct patterns of gene and protein expression elicited by organophosphorus pesticides in Caenorhabditis elegans. Lewis JA, et al. BMC Genomics, 2009 Apr 29. PMID 19402892, Free PMC Article
    3. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
    4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Carboxylesterase type B domain-containing protein
    NP_506508.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      14168360..14171481 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_074107.6 → NP_506508.2  Carboxylesterase type B domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_506508.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      G5EDJ7
      Conserved Domains (1) summary
      pfam00135
      Location:21 → 533
      COesterase; Carboxylesterase family
    Nucleotide Protein
    Heading Accession and Version

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