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    wrt-8 Warthog protein 8 N-product [ Caenorhabditis elegans ]

    Gene ID: 180035, updated on 9-Dec-2024

    Summary

    Official Symbol
    wrt-8
    Official Full Name
    Warthog protein 8 N-product
    Primary source
    WormBase:WBGene00006954
    Locus tag
    CELE_C29F3.2
    See related
    AllianceGenome:WB:WBGene00006954
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable peptidase activity. Predicted to be involved in cell-cell signaling; protein autoprocessing; and system development. Predicted to be located in cell surface; extracellular region; and plasma membrane. Predicted to be active in extracellular matrix. Is expressed in several structures, including P1; P10; P11; P12; and hypodermal cell. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See wrt-8 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    11
    Sequence:
    Chromosome: V; NC_003283.11 (15342054..15344581, complement)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene C-type lectin domain-containing protein Neighboring gene C-type lectin domain-containing protein Neighboring gene DUF2807 domain-containing protein Neighboring gene C-type lectin domain-containing protein

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    enables peptidase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in cell-cell signaling IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in cell-cell signaling NAS
    Non-traceable Author Statement
    more info
    PubMed 
    involved_in multicellular organism development IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in protein autoprocessing IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in protein autoprocessing NAS
    Non-traceable Author Statement
    more info
    PubMed 
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in segment polarity determination NAS
    Non-traceable Author Statement
    more info
    PubMed 
    involved_in system development IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in cell surface IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in extracellular matrix IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
     
    located_in extracellular region NAS
    Non-traceable Author Statement
    more info
    PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in plasma membrane NAS
    Non-traceable Author Statement
    more info
    PubMed 

    General protein information

    Preferred Names
    Warthog protein 8 N-product
    NP_506805.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      15342054..15344581 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_074404.6NP_506805.1  Warthog protein 8 N-product [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_506805.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O45273, Q94130
      Conserved Domains (3) summary
      smart00305
      Location:452495
      HintC; Hint (Hedgehog/Intein) domain C-terminal region
      smart00306
      Location:341446
      HintN; Hint (Hedgehog/Intein) domain N-terminal region
      pfam01079
      Location:330544
      Hint; Hint module