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    tsct-1 Protein tsct-1 [ Caenorhabditis elegans ]

    Gene ID: 188577, updated on 9-Dec-2024

    Summary

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    Official Symbol
    tsct-1
    Official Full Name
    Protein tsct-1
    Primary source
    WormBase:WBGene00011824
    Locus tag
    CELE_T18D3.7
    See related
    AllianceGenome:WB:WBGene00011824
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in regulation of transcription by RNA polymerase II. Is expressed in anal region; body wall musculature; head; neurons; and pharynx. Orthologous to several human genes including TSC22D3 (TSC22 domain family member 3). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See tsct-1 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    7
    Sequence:
    Chromosome: X; NC_003284.9 (12434097..12443915)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene Ovule protein Neighboring gene GATA-type domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Uncharacterized protein Neighboring gene Mitochondrial inner membrane protein Mpv17 Neighboring gene WD repeat-containing protein 89

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003284.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Investigating the role of RIO protein kinases in Caenorhabditis elegans. Mendes TK, et al. PLoS One, 2015. PMID 25688864, Free PMC Article
    2. Prefoldin 6 mediates longevity response from heat shock factor 1 to FOXO in C. elegans. Son HG, et al. Genes Dev, 2018 Dec 1. PMID 30478249, Free PMC Article
    3. A 4D single-cell protein atlas of transcription factors delineates spatiotemporal patterning during embryogenesis. Ma X, et al. Nat Methods, 2021 Aug. PMID 34312566
    4. C. elegans ORFeome version 1.1: experimental verification of the genome annotation and resource for proteome-scale protein expression. Reboul J, et al. Nat Genet, 2003 May. PMID 12679813
    5. A genome-wide study of PDZ-domain interactions in C. elegans reveals a high frequency of non-canonical binding. Lenfant N, et al. BMC Genomics, 2010 Nov 26. PMID 21110867, Free PMC Article

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    Protein tsct-1
    NP_001257192.1
    • Confirmed by transcript evidence
    NP_001366745.1
    • Confirmed by transcript evidence
    NP_001368132.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      12434097..12443915
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001270263.3 → NP_001257192.1  Protein tsct-1 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001257192.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      I2HAB1, I2HAB2, Q22544
      Conserved Domains (1) summary
      pfam01166
      Location:210 → 266
      TSC22; TSC-22/dip/bun family

    2. NM_001381118.1 → NP_001368132.1  Protein tsct-1 [Caenorhabditis elegans]

      Status: REVIEWED

      Conserved Domains (1) summary
      pfam01166
      Location:196 → 252
      TSC22; TSC-22/dip/bun family

    3. NM_001381119.1 → NP_001366745.1  Protein tsct-1 [Caenorhabditis elegans]

      Status: REVIEWED

      Conserved Domains (1) summary
      pfam01166
      Location:72 → 128
      TSC22; TSC-22/dip/bun family
    Nucleotide Protein
    Heading Accession and Version

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