W03F11.4 WSN domain-containing protein [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: W03F11.4
Official Full Name: WSN domain-containing protein
Primary source: WormBase:WBGene00021007
Locus tag: CELE_W03F11.4
See related: AllianceGenome:WB:WBGene00021007
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable protein tyrosine phosphatase activity. Predicted to be involved in protein dephosphorylation. Predicted to be located in membrane. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See W03F11.4 in Genome Data Viewer

Location:: chromosome: I

Exon count:: 10

Sequence:: Chromosome: I; NC_003279.8 (2235602..2241252, complement)

Chromosome I - NC_003279.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003279.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

W03F11.4 (e-PCR)
- UniSTS:311110

STS1-109 (e-PCR)
- UniSTS:241593

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables protein tyrosine phosphatase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in protein dephosphorylation	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: WSN domain-containing protein

NP_490945.2

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003279.8 Reference assembly

Range

2235602..2241252 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_058544.6 → NP_490945.2 WSN domain-containing protein [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_490945.2

Status: REVIEWED

UniProtKB/TrEMBL

O01777

Conserved Domains (3) summary

smart00453
Location:47 → 113

WSN; Worm-specific (usually) N-terminal domain

cd00047
Location:966 → 1222

PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...

pfam00102
Location:966 → 1222

Y_phosphatase; Protein-tyrosine phosphatase