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    C24F3.2 protein-tyrosine-phosphatase [ Caenorhabditis elegans ]

    Gene ID: 177903, updated on 9-Dec-2024

    Summary

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    Official Symbol
    C24F3.2
    Official Full Name
    protein-tyrosine-phosphatase
    Primary source
    WormBase:WBGene00007697
    Locus tag
    CELE_C24F3.2
    See related
    AllianceGenome:WB:WBGene00007697
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable protein tyrosine/serine/threonine phosphatase activity. Predicted to be involved in protein dephosphorylation. Predicted to be active in nucleus. Orthologous to human DUSP12 (dual specificity phosphatase 12). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See C24F3.2 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    6
    Sequence:
    Chromosome: IV; NC_003282.8 (10222539..10223745)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Translocating chain-associated membrane protein Neighboring gene ncRNA Neighboring gene Zinc metalloproteinase nas-12 Neighboring gene UPAR/Ly6 domain-containing protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein tyrosine phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein tyrosine/serine/threonine phosphatase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein tyrosine/serine/threonine phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in dephosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in protein dephosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    protein-tyrosine-phosphatase
    NP_501870.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      10222539..10223745
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_069469.7 → NP_501870.1  protein-tyrosine-phosphatase [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_501870.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9XXK8
      Conserved Domains (1) summary
      cd00127
      Location:3 → 143
      DSPc; Dual specificity phosphatases (DSP); Ser/Thr and Tyr protein phosphatases. Structurally similar to tyrosine-specific phosphatases but with a shallower active site cleft and a distinctive active site signature motif, HCxxGxxR. Characterized as VHR- or ...
    Nucleotide Protein
    Heading Accession and Version

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