U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Fat1 FAT atypical cadherin 1 [ Mus musculus (house mouse) ]

    Gene ID: 14107, updated on 27-Nov-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    Fat1provided by MGI
    Official Full Name
    FAT atypical cadherin 1provided by MGI
    Primary source
    MGI:MGI:109168
    See related
    Ensembl:ENSMUSG00000070047 AllianceGenome:MGI:109168
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Fath; mFat1; 2310038E12Rik
    Summary
    Involved in epithelial cell morphogenesis; establishment of epithelial cell apical/basal polarity involved in camera-type eye morphogenesis; and lens development in camera-type eye. Acts upstream of or within actin filament organization; cell-cell adhesion; and establishment or maintenance of cell polarity. Located in cell junction; filopodium; and lamellipodium. Is active in apical plasma membrane. Is expressed in several structures, including alimentary system; central nervous system; embryo ectoderm; embryo mesenchyme; and sensory organ. Used to study facioscapulohumeral muscular dystrophy and nephrotic syndrome. Human ortholog(s) of this gene implicated in colorectal cancer; esophagus squamous cell carcinoma; lung non-small cell carcinoma; lung small cell carcinoma; and oral squamous cell carcinoma. Orthologous to human FAT1 (FAT atypical cadherin 1). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Ubiquitous expression in limb E14.5 (RPKM 20.3), colon adult (RPKM 15.5) and 24 other tissues See more
    Orthologs
    human all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See Fat1 in Genome Data Viewer
    Location:
    8 B1.1; 8 24.81 cM
    Exon count:
    34
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (45386137..45505294)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (44933100..45052257)

    Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene dynein light chain 1, cytoplasmic-like Neighboring gene STARR-seq mESC enhancer starr_21340 Neighboring gene STARR-seq mESC enhancer starr_21342 Neighboring gene STARR-seq mESC enhancer starr_21343 Neighboring gene STARR-seq mESC enhancer starr_21344 Neighboring gene STARR-seq mESC enhancer starr_21345 Neighboring gene STARR-seq mESC enhancer starr_21346 Neighboring gene STARR-seq mESC enhancer starr_21347 Neighboring gene STARR-seq mESC enhancer starr_21348 Neighboring gene predicted gene, 30397 Neighboring gene STARR-seq mESC enhancer starr_21350 Neighboring gene STARR-seq mESC enhancer starr_21351 Neighboring gene STARR-seq mESC enhancer starr_21352 Neighboring gene STARR-seq mESC enhancer starr_21353 Neighboring gene STARR-seq mESC enhancer starr_21356 Neighboring gene STARR-seq mESC enhancer starr_21359 Neighboring gene STARR-seq mESC enhancer starr_21360 Neighboring gene STARR-seq mESC enhancer starr_21361 Neighboring gene predicted gene 9908 Neighboring gene STARR-seq mESC enhancer starr_21364 Neighboring gene cDNA sequence AY512931 Neighboring gene melatonin receptor 1A

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Expression

    Go to the top of the page Help
    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Effects of cyclic tensile strain and microgravity on the distribution of actin fiber and Fat1 cadherin in murine articular chondrocytes. Hatakeyama J, et al. J Biomech, 2021 Dec 2. PMID 34627073
    2. Cloning and expression throughout mouse development of mfat1, a homologue of the Drosophila tumour suppressor gene fat. Cox B, et al. Dev Dyn, 2000 Mar. PMID 10741417
    3. Control of mitochondrial function and cell growth by the atypical cadherin Fat1. Cao LL, et al. Nature, 2016 Nov 24. PMID 27828948, Free PMC Article
    4. Expression and function of the atypical cadherin FAT1 in chronic liver disease. Valletta D, et al. Biochem Biophys Res Commun, 2012 Sep 28. PMID 22959770
    5. n-3 Polyunsaturated Fatty Acids Modulate LPS-Induced ARDS and the Lung-Brain Axis of Communication in Wild-Type versus Fat-1 Mice Genetically Modified for Leukotriene B4 Receptor 1 or Chemerin Receptor 23 Knockout. Hernandez J, et al. Int J Mol Sci, 2023 Aug 31. PMID 37686333, Free PMC Article

    See all (50) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. FAT1 inhibits AML autophagy and proliferation via downregulating ATG4B expression.
      Title: FAT1 inhibits AML autophagy and proliferation via downregulating ATG4B expression.
    2. n-3 Polyunsaturated Fatty Acids Modulate LPS-Induced ARDS and the Lung-Brain Axis of Communication in Wild-Type versus Fat-1 Mice Genetically Modified for Leukotriene B4 Receptor 1 or Chemerin Receptor 23 Knockout.
      Title: n-3 Polyunsaturated Fatty Acids Modulate LPS-Induced ARDS and the Lung-Brain Axis of Communication in Wild-Type versus Fat-1 Mice Genetically Modified for Leukotriene B4 Receptor 1 or Chemerin Receptor 23 Knockout.
    3. Astrocyte-intrinsic and -extrinsic Fat1 activities regulate astrocyte development and angiogenesis in the retina.
      Title: Astrocyte-intrinsic and -extrinsic Fat1 activities regulate astrocyte development and angiogenesis in the retina.
    4. Postnatal expression profiles of atypical cadherin FAT1 suggest its role in autism.
      Title: Postnatal expression profiles of atypical cadherin FAT1 suggest its role in autism.
    5. Effects of cyclic tensile strain and microgravity on the distribution of actin fiber and Fat1 cadherin in murine articular chondrocytes.
      Title: Effects of cyclic tensile strain and microgravity on the distribution of actin fiber and Fat1 cadherin in murine articular chondrocytes.
    6. Fat1 deletion promotes hybrid EMT state, tumour stemness and metastasis.
      Title: Fat1 deletion promotes hybrid EMT state, tumour stemness and metastasis.
    7. coordinates the coupling of muscular and neuronal morphogenesis by playing distinct but complementary actions in several cell types
      Title: Tissue-specific activities of the Fat1 cadherin cooperate to control neuromuscular morphogenesis.
    8. studies suggest that Fat1 controls mitochondrial activity to restrain cell growth during the reparative, proliferative state induced by vascular injury. Given recent reports linking Fat1 to cancer, abnormal kidney and muscle development, and neuropsychiatric disease, this Fat1 function may have importance in other settings of altered cell growth and metabolism
      Title: Control of mitochondrial function and cell growth by the atypical cadherin Fat1.
    9. Fat1 deletion in podocytes induces abnormal glomerular filtration barrier development leading to podocyte foot process effacement. Fat1 knockdown in renal tubular cells reduces migration, decreases active RAC1/CDC42 and induces defects in lumen formation.
      Title: FAT1 mutations cause a glomerulotubular nephropathy.
    10. Fat1 interacts with Fat4 to regulate neural tube closure, neural progenitor proliferation and apical constriction during mouse brain development.
      Title: Fat1 interacts with Fat4 to regulate neural tube closure, neural progenitor proliferation and apical constriction during mouse brain development.
    Submit: New GeneRIF Correction See all GeneRIFs (17)

    Variation

    Go to the top of the page Help

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    Go to the top of the page

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within actin filament organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in camera-type eye development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in camera-type eye morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in cell-cell adhesion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within cell-cell adhesion IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in epithelial cell morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in establishment of epithelial cell apical/basal polarity involved in camera-type eye morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within establishment or maintenance of cell polarity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in establishment or maintenance of epithelial cell apical/basal polarity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in lens development in camera-type eye IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in positive regulation of vascular associated smooth muscle cell migration ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    is_active_in apical plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cell junction IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cell-cell junction ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in filopodium IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in lamellipodium IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in perinuclear region of cytoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    protocadherin Fat 1
    Names
    FAT tumor suppressor homolog 1
    fat 1 cadherin

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001081286.3 → NP_001074755.2  protocadherin Fat 1 precursor

      See identical proteins and their annotated locations for NP_001074755.2

      Status: VALIDATED

      Source sequence(s)
      AC119214, AC158352
      Consensus CDS
      CCDS52547.1
      UniProtKB/TrEMBL
      F2Z4A3, Q9QXA3
      Related
      ENSMUSP00000140596.2, ENSMUST00000191428.7
      Conserved Domains (5) summary
      cd11304
      Location:3236 → 3333
      Cadherin_repeat; Cadherin tandem repeat domain
      smart00282
      Location:3856 → 3987
      LamG; Laminin G domain
      cd00054
      Location:4129 → 4165
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      pfam00008
      Location:4095 → 4125
      EGF; EGF-like domain
      cl29226
      Location:278 → 357
      Cadherin; Cadherin domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000074.7 Reference GRCm39 C57BL/6J

      Range
      45386137..45505294
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006509267.4 → XP_006509330.1  protocadherin Fat 1 isoform X1

      See identical proteins and their annotated locations for XP_006509330.1

      UniProtKB/TrEMBL
      A0A1L1SQU7, Q9QXA3
      Conserved Domains (5) summary
      cd11304
      Location:3259 → 3356
      Cadherin_repeat; Cadherin tandem repeat domain
      smart00282
      Location:3879 → 4010
      LamG; Laminin G domain
      cd00054
      Location:4152 → 4188
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      pfam00008
      Location:4118 → 4148
      EGF; EGF-like domain
      cl29226
      Location:278 → 357
      Cadherin; Cadherin domain

    2. XM_006509270.4 → XP_006509333.1  protocadherin Fat 1 isoform X2

      UniProtKB/TrEMBL
      Q9QXA3
      Conserved Domains (5) summary
      cd11304
      Location:3259 → 3356
      Cadherin_repeat; Cadherin tandem repeat domain
      smart00282
      Location:3879 → 4010
      LamG; Laminin G domain
      cd00054
      Location:4152 → 4188
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      pfam00008
      Location:4118 → 4148
      EGF; EGF-like domain
      cl29226
      Location:278 → 357
      Cadherin; Cadherin domain

    3. XM_006509272.4 → XP_006509335.1  protocadherin Fat 1 isoform X4

      UniProtKB/TrEMBL
      Q9QXA3
      Conserved Domains (5) summary
      cd11304
      Location:3259 → 3356
      Cadherin_repeat; Cadherin tandem repeat domain
      smart00282
      Location:3879 → 4010
      LamG; Laminin G domain
      cd00054
      Location:4152 → 4188
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      pfam00008
      Location:4118 → 4148
      EGF; EGF-like domain
      cl29226
      Location:278 → 357
      Cadherin; Cadherin domain

    4. XM_006509273.4 → XP_006509336.1  protocadherin Fat 1 isoform X5

      UniProtKB/TrEMBL
      Q9QXA3
      Conserved Domains (4) summary
      cd11304
      Location:3259 → 3356
      Cadherin_repeat; Cadherin tandem repeat domain
      smart00282
      Location:3879 → 4010
      LamG; Laminin G domain
      cd00054
      Location:4115 → 4151
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      cl29226
      Location:278 → 357
      Cadherin; Cadherin domain

    5. XM_036153756.1 → XP_036009649.1  protocadherin Fat 1 isoform X7

      UniProtKB/TrEMBL
      Q9QXA3
      Conserved Domains (4) summary
      cd11304
      Location:3259 → 3356
      Cadherin_repeat; Cadherin tandem repeat domain
      smart00282
      Location:3879 → 4010
      LamG; Laminin G domain
      cd00054
      Location:4115 → 4151
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      cl29226
      Location:278 → 357
      Cadherin; Cadherin domain

    6. XM_017312564.2 → XP_017168053.1  protocadherin Fat 1 isoform X8

      UniProtKB/TrEMBL
      Q9QXA3
      Conserved Domains (4) summary
      cd11304
      Location:3259 → 3356
      Cadherin_repeat; Cadherin tandem repeat domain
      smart00282
      Location:3879 → 4010
      LamG; Laminin G domain
      cd00054
      Location:4115 → 4151
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      cl29226
      Location:278 → 357
      Cadherin; Cadherin domain

    7. XM_006509271.4 → XP_006509334.1  protocadherin Fat 1 isoform X3

      UniProtKB/TrEMBL
      Q9QXA3
      Conserved Domains (5) summary
      cd11304
      Location:3236 → 3333
      Cadherin_repeat; Cadherin tandem repeat domain
      smart00282
      Location:3856 → 3987
      LamG; Laminin G domain
      cd00054
      Location:4129 → 4165
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      pfam00008
      Location:4095 → 4125
      EGF; EGF-like domain
      cl29226
      Location:278 → 357
      Cadherin; Cadherin domain

    8. XM_006509277.4 → XP_006509340.1  protocadherin Fat 1 isoform X10

      UniProtKB/TrEMBL
      A0A087WRT4, Q9QXA3
      Related
      ENSMUSP00000140765.3, ENSMUST00000189017.8
      Conserved Domains (5) summary
      cd11304
      Location:3236 → 3333
      Cadherin_repeat; Cadherin tandem repeat domain
      smart00282
      Location:3856 → 3987
      LamG; Laminin G domain
      cd00054
      Location:4129 → 4165
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      pfam00008
      Location:4095 → 4125
      EGF; EGF-like domain
      cl29226
      Location:278 → 357
      Cadherin; Cadherin domain

    9. XM_006509276.5 → XP_006509339.1  protocadherin Fat 1 isoform X9

      See identical proteins and their annotated locations for XP_006509339.1

      UniProtKB/TrEMBL
      Q9QXA3
      Conserved Domains (5) summary
      cd11304
      Location:3259 → 3356
      Cadherin_repeat; Cadherin tandem repeat domain
      smart00282
      Location:3879 → 4010
      LamG; Laminin G domain
      cd00054
      Location:4152 → 4188
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      pfam00008
      Location:4118 → 4148
      EGF; EGF-like domain
      cl29226
      Location:278 → 357
      Cadherin; Cadherin domain

    10. XM_030243288.2 → XP_030099148.1  protocadherin Fat 1 isoform X1

      UniProtKB/TrEMBL
      A0A1L1SQU7, Q9QXA3
      Conserved Domains (5) summary
      cd11304
      Location:3259 → 3356
      Cadherin_repeat; Cadherin tandem repeat domain
      smart00282
      Location:3879 → 4010
      LamG; Laminin G domain
      cd00054
      Location:4152 → 4188
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      pfam00008
      Location:4118 → 4148
      EGF; EGF-like domain
      cl29226
      Location:278 → 357
      Cadherin; Cadherin domain

    11. XM_011242173.4 → XP_011240475.1  protocadherin Fat 1 isoform X1

      See identical proteins and their annotated locations for XP_011240475.1

      UniProtKB/TrEMBL
      A0A1L1SQU7, Q9QXA3
      Conserved Domains (5) summary
      cd11304
      Location:3259 → 3356
      Cadherin_repeat; Cadherin tandem repeat domain
      smart00282
      Location:3879 → 4010
      LamG; Laminin G domain
      cd00054
      Location:4152 → 4188
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      pfam00008
      Location:4118 → 4148
      EGF; EGF-like domain
      cl29226
      Location:278 → 357
      Cadherin; Cadherin domain

    12. XM_036153754.1 → XP_036009647.1  protocadherin Fat 1 isoform X1

      UniProtKB/TrEMBL
      A0A1L1SQU7, Q9QXA3
      Conserved Domains (5) summary
      cd11304
      Location:3259 → 3356
      Cadherin_repeat; Cadherin tandem repeat domain
      smart00282
      Location:3879 → 4010
      LamG; Laminin G domain
      cd00054
      Location:4152 → 4188
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      pfam00008
      Location:4118 → 4148
      EGF; EGF-like domain
      cl29226
      Location:278 → 357
      Cadherin; Cadherin domain

    13. XM_030243287.2 → XP_030099147.1  protocadherin Fat 1 isoform X1

      UniProtKB/TrEMBL
      A0A1L1SQU7, Q9QXA3
      Conserved Domains (5) summary
      cd11304
      Location:3259 → 3356
      Cadherin_repeat; Cadherin tandem repeat domain
      smart00282
      Location:3879 → 4010
      LamG; Laminin G domain
      cd00054
      Location:4152 → 4188
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      pfam00008
      Location:4118 → 4148
      EGF; EGF-like domain
      cl29226
      Location:278 → 357
      Cadherin; Cadherin domain

    14. XM_006509268.5 → XP_006509331.1  protocadherin Fat 1 isoform X1

      See identical proteins and their annotated locations for XP_006509331.1

      UniProtKB/TrEMBL
      A0A1L1SQU7, Q9QXA3
      Related
      ENSMUSP00000149194.2, ENSMUST00000215588.2
      Conserved Domains (5) summary
      cd11304
      Location:3259 → 3356
      Cadherin_repeat; Cadherin tandem repeat domain
      smart00282
      Location:3879 → 4010
      LamG; Laminin G domain
      cd00054
      Location:4152 → 4188
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      pfam00008
      Location:4118 → 4148
      EGF; EGF-like domain
      cl29226
      Location:278 → 357
      Cadherin; Cadherin domain

    15. XM_036153755.1 → XP_036009648.1  protocadherin Fat 1 isoform X3

      UniProtKB/TrEMBL
      Q9QXA3
      Conserved Domains (5) summary
      cd11304
      Location:3236 → 3333
      Cadherin_repeat; Cadherin tandem repeat domain
      smart00282
      Location:3856 → 3987
      LamG; Laminin G domain
      cd00054
      Location:4129 → 4165
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      pfam00008
      Location:4095 → 4125
      EGF; EGF-like domain
      cl29226
      Location:278 → 357
      Cadherin; Cadherin domain

    RNA

    1. XR_001778405.2 RNA Sequence

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_010179.1: Suppressed sequence

      Description
      NM_010179.1: This RefSeq record was removed by NCBI staff. Contact [email protected] for further information.
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
    Molecular Biology Databases
    Research Materials
    Tools