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    ZBTB48 zinc finger and BTB domain containing 48 [ Bos taurus (domestic cattle) ]

    Gene ID: 534608, updated on 30-Jan-2025

    Summary

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    Official Symbol
    ZBTB48provided by VGNC
    Official Full Name
    zinc finger and BTB domain containing 48provided by VGNC
    Primary source
    VGNC:VGNC:37085
    See related
    BGD:BT23097; EnsemblRapid:ENSBTAG00070017907
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See ZBTB48 in Genome Data Viewer
    Location:
    chromosome: 16
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 16 NC_037343.1 (46815302..46823463, complement)

    Chromosome 16 - NC_037343.1Genomic Context describing neighboring genes Neighboring gene PHD finger protein 13 Neighboring gene kelch like family member 21 Neighboring gene taste 1 receptor member 1 Neighboring gene nucleolar protein 9

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037343.1 Chromosome 16 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    telomere zinc finger-associated protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001192979.1 → NP_001179908.1  telomere zinc finger-associated protein

      See identical proteins and their annotated locations for NP_001179908.1

      Status: PROVISIONAL

      Source sequence(s)
      NKLS02000016
      UniProtKB/TrEMBL
      A0A3Q1MEW4
      Conserved Domains (7) summary
      COG5048
      Location:463 → 524
      COG5048; FOG: Zn-finger [General function prediction only]
      COG5189
      Location:374 → 459
      SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
      sd00017
      Location:467 → 487
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:409 → 425
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:578 → 600
      zf-C2H2; Zinc finger, C2H2 type
      pfam00651
      Location:16 → 114
      BTB; BTB/POZ domain
      pfam13465
      Location:565 → 589
      zf-H2C2_2; Zinc-finger double domain

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037343.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      46815302..46823463 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024976331.2 → XP_024832099.1  telomere zinc finger-associated protein isoform X2

      UniProtKB/TrEMBL
      A0A3Q1MEW4
      Related
      ENSBTAP00070023936.1, ENSBTAT00070040380.1
      Conserved Domains (7) summary
      COG5048
      Location:463 → 524
      COG5048; FOG: Zn-finger [General function prediction only]
      COG5189
      Location:374 → 459
      SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
      sd00017
      Location:467 → 487
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:409 → 425
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:578 → 600
      zf-C2H2; Zinc finger, C2H2 type
      pfam00651
      Location:16 → 114
      BTB; BTB/POZ domain
      pfam13465
      Location:565 → 589
      zf-H2C2_2; Zinc-finger double domain

    2. XM_015475152.3 → XP_015330638.1  telomere zinc finger-associated protein isoform X1

      UniProtKB/TrEMBL
      A0A3Q1MEW4, E1BPM6
      Related
      ENSBTAP00070023927.1, ENSBTAT00070040370.1
      Conserved Domains (7) summary
      smart00225
      Location:27 → 114
      BTB; Broad-Complex, Tramtrack and Bric a brac
      COG5048
      Location:464 → 525
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:468 → 488
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:410 → 426
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:579 → 601
      zf-C2H2; Zinc finger, C2H2 type
      pfam00651
      Location:16 → 114
      BTB; BTB/POZ domain
      pfam13465
      Location:480 → 505
      zf-H2C2_2; Zinc-finger double domain

    3. XM_005217100.5 → XP_005217157.1  telomere zinc finger-associated protein isoform X1

      UniProtKB/TrEMBL
      A0A3Q1MEW4, E1BPM6
      Conserved Domains (7) summary
      smart00225
      Location:27 → 114
      BTB; Broad-Complex, Tramtrack and Bric a brac
      COG5048
      Location:464 → 525
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:468 → 488
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:410 → 426
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:579 → 601
      zf-C2H2; Zinc finger, C2H2 type
      pfam00651
      Location:16 → 114
      BTB; BTB/POZ domain
      pfam13465
      Location:480 → 505
      zf-H2C2_2; Zinc-finger double domain
    Nucleotide Protein Strain
    Heading Accession and Version

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