PRP6 prolactin-related protein VI [Bos taurus (domestic cattle)] - Gene

Summary

Gene symbol: PRP6
Gene description: prolactin-related protein VI
See related: BGD:BT21606; EnsemblRapid:ENSBTAG00070005366
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Bos taurus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Also known as: GHE2
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Genomic context

Location:: chromosome: 23

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
RS_2024_12	current	ARS-UCD2.0 (GCF_002263795.3)	23	NC_037350.1 (34713638..34726004, complement)

Chromosome 23 - NC_037350.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_037350.1 Chromosome 23 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Dominette sequence data
BioProject: PRJNA294306
Analysis date: Tue Dec 17 08:57:05 2024

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Identified novel prolactin-related proteins (PRPs) in caprine placenta, and indicated that PRP genes in caprine placenta have coordination functions for gestation, as they do in bovine.
Title: Gene expression profiles of novel caprine placental prolactin-related proteins similar to bovine placental prolactin-related proteins.

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables hormone activity	IEA Inferred from Electronic Annotation more info	PubMed
enables prolactin receptor binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in female pregnancy	IEA Inferred from Electronic Annotation more info	PubMed
involved_in mammary gland development	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of cell population proliferation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of lactation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of receptor signaling pathway via JAK-STAT	IEA Inferred from Electronic Annotation more info	PubMed
involved_in response to nutrient levels	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in extracellular region	IEA Inferred from Electronic Annotation more info	PubMed
located_in extracellular space	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: prolactin-related protein VI

Names: growth hormone E2; prolactin-like protein; prolactin-related protein 6

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_205778.1 → NP_991347.1 prolactin-related protein VI precursor

See identical proteins and their annotated locations for NP_991347.1

Status: PROVISIONAL

Source sequence(s)

X59504

UniProtKB/TrEMBL

Q28135, Q2PEE7

Related

ENSBTAP00070006927.1, ENSBTAT00070012259.1

Conserved Domains (1) summary

cd10288
Location:40 → 236

prolactin_like; Prolactin (PRL or PRL1), chorionic somatomammotropin, and related pituitary gland hormones