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    MDH1B malate dehydrogenase 1B [ Bos taurus (domestic cattle) ]

    Gene ID: 527943, updated on 27-Dec-2024

    Summary

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    Official Symbol
    MDH1Bprovided by VGNC
    Official Full Name
    malate dehydrogenase 1Bprovided by VGNC
    Primary source
    VGNC:VGNC:31334
    See related
    Ensembl:ENSBTAG00000016192
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See MDH1B in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 2 NC_037329.1 (95032176..95064685, complement)

    Chromosome 2 - NC_037329.1Genomic Context describing neighboring genes Neighboring gene family with sequence similarity 237 member A Neighboring gene dystrotelin Neighboring gene FAST kinase domains 2 Neighboring gene large ribosomal subunit protein uL14-like

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037329.1 Chromosome 2 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC155115

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables L-malate dehydrogenase (NAD+) activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in NADH metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in malate metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in oxaloacetate metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in tricarboxylic acid cycle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    putative malate dehydrogenase 1B
    Names
    malate dehydrogenase 1B, NAD (soluble)
    NP_001076921.1
    XP_005202787.1
    XP_005202788.1
    XP_024831035.1
    XP_024831042.1
    XP_024831045.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001083452.1 → NP_001076921.1  putative malate dehydrogenase 1B

      See identical proteins and their annotated locations for NP_001076921.1

      Status: PROVISIONAL

      Source sequence(s)
      BC133372
      UniProtKB/Swiss-Prot
      A3KMX7
      UniProtKB/TrEMBL
      A0AAF6ZD46
      Related
      ENSBTAP00000038086.4, ENSBTAT00000038271.5
      Conserved Domains (2) summary
      TIGR01759
      Location:131 → 457
      MalateDH-SF1; malate dehydrogenase
      cl21454
      Location:9 → 459
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037329.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      95032176..95064685 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005202731.5 → XP_005202788.1  putative malate dehydrogenase 1B isoform X2

      UniProtKB/TrEMBL
      A0A3Q1MIE5, A0AAA9T5J5
      Related
      ENSBTAP00000068936.2, ENSBTAT00000074267.2
      Conserved Domains (1) summary
      cl21454
      Location:9 → 405
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    2. XM_005202730.5 → XP_005202787.1  putative malate dehydrogenase 1B isoform X1

      UniProtKB/TrEMBL
      A0A3Q1MGA1, A0AAA9T5J5
      Related
      ENSBTAP00000070202.1, ENSBTAT00000082652.2
      Conserved Domains (2) summary
      TIGR01759
      Location:131 → 457
      MalateDH-SF1; malate dehydrogenase
      cl21454
      Location:9 → 459
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    3. XM_024975277.2 → XP_024831045.1  putative malate dehydrogenase 1B isoform X4

      Conserved Domains (1) summary
      cl21454
      Location:2 → 299
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    4. XM_024975267.2 → XP_024831035.1  putative malate dehydrogenase 1B isoform X3

      Conserved Domains (1) summary
      cl21454
      Location:3 → 324
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    5. XM_024975274.2 → XP_024831042.1  putative malate dehydrogenase 1B isoform X4

      Conserved Domains (1) summary
      cl21454
      Location:2 → 299
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A3KMX7.1 GenPept UniProtKB/Swiss-Prot:A3KMX7

    Gene LinkOut

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    Research Materials