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    LRRN1 leucine rich repeat neuronal 1 [ Bos taurus (domestic cattle) ]

    Gene ID: 539619, updated on 29-Jan-2025

    Summary

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    Official Symbol
    LRRN1provided by VGNC
    Official Full Name
    leucine rich repeat neuronal 1provided by VGNC
    Primary source
    VGNC:VGNC:31039
    See related
    BGD:BT18527; Ensembl:ENSBTAG00000001176
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Also known as
    NLRR-1
    Orthologs
    human mouse all
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    Genomic context

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    See LRRN1 in Genome Data Viewer
    Location:
    chromosome: 22
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 22 NC_037349.1 (22468872..22512268, complement)

    Chromosome 22 - NC_037349.1Genomic Context describing neighboring genes Neighboring gene SET domain without mariner transposase fusion Neighboring gene high mobility group protein B3-like Neighboring gene uncharacterized LOC104975528 Neighboring gene uncharacterized LOC132343491 Neighboring gene uncharacterized LOC107131666 Neighboring gene uncharacterized LOC132343493

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037349.1 Chromosome 22 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular matrix IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    leucine-rich repeat neuronal protein 1
    Names
    leucine-rich repeats and calponin homology (CH) domain containing 4
    neuronal leucine-rich repeat protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001080738.1 → NP_001074207.1  leucine-rich repeat neuronal protein 1 precursor

      See identical proteins and their annotated locations for NP_001074207.1

      Status: PROVISIONAL

      Source sequence(s)
      EF093509
      UniProtKB/Swiss-Prot
      A0N0X6
      UniProtKB/TrEMBL
      A0AAA9S522
      Related
      ENSBTAP00070027022.1, ENSBTAT00070044946.1
      Conserved Domains (7) summary
      smart00060
      Location:531 → 600
      FN3; Fibronectin type 3 domain
      smart00082
      Location:371 → 419
      LRRCT; Leucine rich repeat C-terminal domain
      sd00031
      Location:339 → 362
      LRR_1; leucine-rich repeat [structural motif]
      sd00033
      Location:97 → 120
      LRR_RI; leucine-rich repeat [structural motif]
      pfam13855
      Location:119 → 179
      LRR_8; Leucine rich repeat
      cl26018
      Location:34 → 306
      NEL; C-terminal novel E3 ligase, LRR-interacting
      cl28434
      Location:429 → 516
      I-set; Immunoglobulin I-set domain

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037349.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      22468872..22512268 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005222668.5 → XP_005222725.1  leucine-rich repeat neuronal protein 1 isoform X1

      See identical proteins and their annotated locations for XP_005222725.1

      UniProtKB/Swiss-Prot
      A0N0X6
      UniProtKB/TrEMBL
      A0AAA9S522
      Related
      ENSBTAP00070027040.1, ENSBTAT00070044966.1
      Conserved Domains (7) summary
      smart00060
      Location:531 → 600
      FN3; Fibronectin type 3 domain
      smart00082
      Location:371 → 419
      LRRCT; Leucine rich repeat C-terminal domain
      sd00031
      Location:339 → 362
      LRR_1; leucine-rich repeat [structural motif]
      sd00033
      Location:97 → 120
      LRR_RI; leucine-rich repeat [structural motif]
      pfam13855
      Location:119 → 179
      LRR_8; Leucine rich repeat
      cl26018
      Location:34 → 306
      NEL; C-terminal novel E3 ligase, LRR-interacting
      cl28434
      Location:429 → 516
      I-set; Immunoglobulin I-set domain

    2. XM_005222669.5 → XP_005222726.1  leucine-rich repeat neuronal protein 1 isoform X1

      See identical proteins and their annotated locations for XP_005222726.1

      UniProtKB/Swiss-Prot
      A0N0X6
      UniProtKB/TrEMBL
      A0AAA9S522
      Related
      ENSBTAP00070027032.1, ENSBTAT00070044957.1
      Conserved Domains (7) summary
      smart00060
      Location:531 → 600
      FN3; Fibronectin type 3 domain
      smart00082
      Location:371 → 419
      LRRCT; Leucine rich repeat C-terminal domain
      sd00031
      Location:339 → 362
      LRR_1; leucine-rich repeat [structural motif]
      sd00033
      Location:97 → 120
      LRR_RI; leucine-rich repeat [structural motif]
      pfam13855
      Location:119 → 179
      LRR_8; Leucine rich repeat
      cl26018
      Location:34 → 306
      NEL; C-terminal novel E3 ligase, LRR-interacting
      cl28434
      Location:429 → 516
      I-set; Immunoglobulin I-set domain

    RNA

    1. XR_814472.4 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0N0X6.1 GenPept UniProtKB/Swiss-Prot:A0N0X6

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials