METTL21A methyltransferase 21A, HSPA lysine [Bos taurus (domestic cattle)] - Gene

Summary

Official Symbol: METTL21Aprovided by VGNC
Official Full Name: methyltransferase 21A, HSPA lysineprovided by VGNC
Primary source: VGNC:VGNC:31406
See related: Ensembl:ENSBTAG00000052083
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Bos taurus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Also known as: FAM119A
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 2

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
RS_2024_12	current	ARS-UCD2.0 (GCF_002263795.3)	2	NC_037329.1 (95837012..95918879, complement)

Chromosome 2 - NC_037329.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_037329.1 Chromosome 2 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Dominette sequence data
BioProject: PRJNA294306
Analysis date: Tue Dec 17 08:57:05 2024

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables protein-lysine N-methyltransferase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in peptidyl-lysine methylation	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info	PubMed
located_in cytosol	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: protein N-lysine methyltransferase METTL21A

Names: family with sequence similarity 119, member A; methyltransferase like 21A; methyltransferase-like protein 21A; protein-lysine methyltransferase METTL21A

NP_001076987.1

EC 2.1.1.-

XP_005202816.1

EC 2.1.1.-

XP_005202817.1

EC 2.1.1.-

XP_024833725.1

EC 2.1.1.-

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001083518.2 → NP_001076987.1 protein N-lysine methyltransferase METTL21A

See identical proteins and their annotated locations for NP_001076987.1

Status: PROVISIONAL

Source sequence(s)

BC123706

UniProtKB/Swiss-Prot

A4FV42

UniProtKB/TrEMBL

A0A3Q1MDM9

Related

ENSBTAP00000069043.2, ENSBTAT00000082056.2

Conserved Domains (1) summary

cl17173
Location:25 → 190

AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

NC_037329.1 Reference ARS-UCD2.0 Primary Assembly

Range

95837012..95918879 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_005202759.5 → XP_005202816.1 protein N-lysine methyltransferase METTL21A isoform X1

See identical proteins and their annotated locations for XP_005202816.1

UniProtKB/Swiss-Prot

A4FV42

UniProtKB/TrEMBL

A0A3Q1MDM9

Conserved Domains (1) summary

cl17173
Location:25 → 190

AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...
XM_005202760.5 → XP_005202817.1 protein N-lysine methyltransferase METTL21A isoform X1

See identical proteins and their annotated locations for XP_005202817.1

UniProtKB/Swiss-Prot

A4FV42

UniProtKB/TrEMBL

A0A3Q1MDM9

Conserved Domains (1) summary

cl17173
Location:25 → 190

AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...
XM_024977957.2 → XP_024833725.1 protein N-lysine methyltransferase METTL21A isoform X1

UniProtKB/Swiss-Prot

A4FV42

UniProtKB/TrEMBL

A0A3Q1MDM9

Conserved Domains (1) summary

cl17173
Location:25 → 190

AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...