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    PLEKHG1 pleckstrin homology and RhoGEF domain containing G1 [ Bos taurus (domestic cattle) ]

    Gene ID: 525772, updated on 30-Jan-2025

    Summary

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    Official Symbol
    PLEKHG1provided by VGNC
    Official Full Name
    pleckstrin homology and RhoGEF domain containing G1provided by VGNC
    Primary source
    VGNC:VGNC:33014
    See related
    BGD:BT13208; EnsemblRapid:ENSBTAG00070013205
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See PLEKHG1 in Genome Data Viewer
    Location:
    chromosome: 9
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 9 NC_037336.1 (87717511..87966379)

    Chromosome 9 - NC_037336.1Genomic Context describing neighboring genes Neighboring gene retinoic acid early transcript 1E Neighboring gene iodotyrosine deiodinase Neighboring gene uncharacterized LOC132346137 Neighboring gene small nucleolar RNA SNORA70 Neighboring gene methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037336.1 Chromosome 9 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables guanyl-nucleotide exchange factor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables small GTPase binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    pleckstrin homology domain-containing family G member 1
    Names
    pleckstrin homology domain containing, family G (with RhoGef domain) member 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001205921.2 → NP_001192850.1  pleckstrin homology domain-containing family G member 1

      Status: PROVISIONAL

      Source sequence(s)
      NKLS02000009
      UniProtKB/TrEMBL
      A0A3Q1NBN2
      Related
      ENSBTAP00070018139.1, ENSBTAT00070029945.1
      Conserved Domains (2) summary
      cd13243
      Location:272 → 417
      PH_PLEKHG1_G2_G3; Pleckstrin homology domain-containing family G members 1, 2, and 3 pleckstrin homology (PH) domain
      pfam00621
      Location:116 → 290
      RhoGEF; RhoGEF domain

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037336.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      87717511..87966379
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024996654.2 → XP_024852422.1  pleckstrin homology domain-containing family G member 1 isoform X3

      UniProtKB/TrEMBL
      A0A3Q1NBN2
      Related
      ENSBTAP00070018219.1, ENSBTAT00070030143.1
      Conserved Domains (2) summary
      cd13243
      Location:272 → 417
      PH_PLEKHG1_G2_G3; Pleckstrin homology domain-containing family G members 1, 2, and 3 pleckstrin homology (PH) domain
      pfam00621
      Location:116 → 290
      RhoGEF; RhoGEF domain

    2. XM_024996651.2 → XP_024852419.1  pleckstrin homology domain-containing family G member 1 isoform X1

      UniProtKB/TrEMBL
      A0A3Q1M261, A0AAA9SF51
      Related
      ENSBTAP00070018168.1, ENSBTAT00070030035.1
      Conserved Domains (2) summary
      cd13243
      Location:369 → 514
      PH_PLEKHG1_G2_G3; Pleckstrin homology domain-containing family G members 1, 2, and 3 pleckstrin homology (PH) domain
      pfam00621
      Location:213 → 387
      RhoGEF; RhoGEF domain

    3. XM_024996655.2 → XP_024852423.1  pleckstrin homology domain-containing family G member 1 isoform X3

      UniProtKB/TrEMBL
      A0A3Q1NBN2
      Conserved Domains (2) summary
      cd13243
      Location:272 → 417
      PH_PLEKHG1_G2_G3; Pleckstrin homology domain-containing family G members 1, 2, and 3 pleckstrin homology (PH) domain
      pfam00621
      Location:116 → 290
      RhoGEF; RhoGEF domain

    4. XM_024996658.2 → XP_024852426.1  pleckstrin homology domain-containing family G member 1 isoform X3

      UniProtKB/TrEMBL
      A0A3Q1NBN2
      Conserved Domains (2) summary
      cd13243
      Location:272 → 417
      PH_PLEKHG1_G2_G3; Pleckstrin homology domain-containing family G members 1, 2, and 3 pleckstrin homology (PH) domain
      pfam00621
      Location:116 → 290
      RhoGEF; RhoGEF domain

    5. XM_024996653.2 → XP_024852421.1  pleckstrin homology domain-containing family G member 1 isoform X2

      UniProtKB/TrEMBL
      A0A3Q1NBN2, F1MRP8
      Related
      ENSBTAP00070018147.1, ENSBTAT00070029977.1
      Conserved Domains (2) summary
      cd13243
      Location:328 → 473
      PH_PLEKHG1_G2_G3; Pleckstrin homology domain-containing family G members 1, 2, and 3 pleckstrin homology (PH) domain
      pfam00621
      Location:172 → 346
      RhoGEF; RhoGEF domain
    Nucleotide Protein Strain
    Heading Accession and Version

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