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    APEH acylaminoacyl-peptide hydrolase [ Bos taurus (domestic cattle) ]

    Gene ID: 514666, updated on 29-Jan-2025

    Summary

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    Official Symbol
    APEHprovided by VGNC
    Official Full Name
    acylaminoacyl-peptide hydrolaseprovided by VGNC
    Primary source
    VGNC:VGNC:26010
    See related
    BGD:BT16286; Ensembl:ENSBTAG00000011583
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Also known as
    APH; AARE
    Orthologs
    human mouse all
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    Genomic context

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    See APEH in Genome Data Viewer
    Location:
    chromosome: 22
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 22 NC_037349.1 (50515197..50523680, complement)

    Chromosome 22 - NC_037349.1Genomic Context describing neighboring genes Neighboring gene GDP-mannose pyrophosphorylase B Neighboring gene ring finger protein 123 Neighboring gene adhesion molecule with Ig like domain 3 Neighboring gene macrophage stimulating 1 Neighboring gene bassoon presynaptic cytomatrix protein Neighboring gene uncharacterized LOC112443525 Neighboring gene dystroglycan 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037349.1 Chromosome 22 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. Bovine lens acylpeptide hydrolase. Purification and characterization of a tetrameric enzyme resistant to urea denaturation and proteolytic inactivation. Sharma KK, et al. Eur J Biochem, 1993 Sep 1. PMID 8375399
    2. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Clone Names

    • MGC139504

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables serine-type endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    acylamino-acid-releasing enzyme
    Names
    Acyl-peptide hydrolase
    Acylaminoacyl-peptidase
    N-acylaminoacyl-peptide hydrolase
    NP_001076900.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001083431.1 → NP_001076900.1  acylamino-acid-releasing enzyme

      See identical proteins and their annotated locations for NP_001076900.1

      Status: PROVISIONAL

      Source sequence(s)
      BC123400
      UniProtKB/Swiss-Prot
      A4FUX4, P80227
      UniProtKB/TrEMBL
      A0AAF6YW75
      Related
      ENSBTAP00070049007.1, ENSBTAT00070080854.1
      Conserved Domains (1) summary
      COG1506
      Location:155 → 730
      DAP2; Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism]

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037349.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      50515197..50523680 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P80227.2 GenPept UniProtKB/Swiss-Prot:P80227

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