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    DERL3 derlin 3 [ Bos taurus (domestic cattle) ]

    Gene ID: 614334, updated on 30-Jan-2025

    Summary

    Official Symbol
    DERL3provided by VGNC
    Official Full Name
    derlin 3provided by VGNC
    Primary source
    VGNC:VGNC:28012
    See related
    BGD:BT14886; EnsemblRapid:ENSBTAG00070018102
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
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    Genomic context

    See DERL3 in Genome Data Viewer
    Location:
    chromosome: 17
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 17 NC_037344.1 (71260778..71262858, complement)

    Chromosome 17 - NC_037344.1Genomic Context describing neighboring genes Neighboring gene matrix metallopeptidase 11 Neighboring gene SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 Neighboring gene solute carrier family 2 member 11 Neighboring gene macrophage migration inhibitory factor

    Genomic regions, transcripts, and products

    Genomic Sequence:
    NC_037344.1 Chromosome 17 Reference ARS-UCD2.0 Primary Assembly

    Expression

    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    General gene information

    Markers

    Clone Names

    • MGC142482

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables misfolded protein binding IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    enables ubiquitin-specific protease binding IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in endoplasmic reticulum unfolded protein response IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Component Evidence Code Pubs
    part_of Hrd1p ubiquitin ligase ERAD-L complex IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    located_in endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
    PubMed 

    General protein information

    Preferred Names
    derlin-3
    Names
    Der1-like domain family, member 3
    degradation in endoplasmic reticulum protein 3
    der1-like protein 3

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001076323.2NP_001069791.1  derlin-3

      See identical proteins and their annotated locations for NP_001069791.1

      Status: PROVISIONAL

      Source sequence(s)
      BC120164
      UniProtKB/Swiss-Prot
      Q0P5E4
      UniProtKB/TrEMBL
      A0AAA9TPL1
      Conserved Domains (1) summary
      pfam04511
      Location:13202
      DER1; Der1-like family

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037344.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      71260778..71262858 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005218250.5XP_005218307.1  derlin-3 isoform X1

      UniProtKB/TrEMBL
      A0AAA9TPL1
      Related
      ENSBTAP00070024332.1, ENSBTAT00070040849.1
      Conserved Domains (1) summary
      pfam04511
      Location:13201
      DER1; Der1-like family