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    CPNE8 copine 8 [ Bos taurus (domestic cattle) ]

    Gene ID: 535744, updated on 29-Jan-2025

    Summary

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    Official Symbol
    CPNE8provided by VGNC
    Official Full Name
    copine 8provided by VGNC
    Primary source
    VGNC:VGNC:27664
    See related
    BGD:BT14333; Ensembl:ENSBTAG00000020914
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See CPNE8 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    23
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 5 NC_037332.1 (42193677..42472420)

    Chromosome 5 - NC_037332.1Genomic Context describing neighboring genes Neighboring gene glyceraldehyde-3-phosphate dehydrogenase-like Neighboring gene uncharacterized LOC132345279 Neighboring gene uncharacterized LOC132345280 Neighboring gene uncharacterized LOC112446905 Neighboring gene protein tyrosine phosphatase receptor type R

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037332.1 Chromosome 5 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables calcium-dependent phospholipid binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cellular response to calcium ion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    copine-8

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001098085.2 → NP_001091554.2  copine-8

      Status: VALIDATED

      Source sequence(s)
      NKLS02000005
      UniProtKB/TrEMBL
      A5D784
      Related
      ENSBTAP00070029924.1, ENSBTAT00070050194.1

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037332.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      42193677..42472420
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_010805078.4 → XP_010803380.1  copine-8 isoform X2

      UniProtKB/TrEMBL
      A0AAA9TUD5
      Related
      ENSBTAP00070029898.1, ENSBTAT00070050161.1
      Conserved Domains (3) summary
      cd04047
      Location:170 → 281
      C2B_Copine; C2 domain second repeat in Copine
      cd04048
      Location:36 → 157
      C2A_Copine; C2 domain first repeat in Copine
      cd01459
      Location:291 → 514
      vWA_copine_like; VWA Copine: Copines are phospholipid-binding proteins originally identified in paramecium. They are found in human and orthologues have been found in C. elegans and Arabidopsis Thaliana. None have been found in D. Melanogaster or S. Cereviciae. ...

    2. XM_010805075.4 → XP_010803377.1  copine-8 isoform X1

      See identical proteins and their annotated locations for XP_010803377.1

      UniProtKB/TrEMBL
      A0A3Q1LMG7, A0AAA9TUD5
      Related
      ENSBTAP00070029890.1, ENSBTAT00070050152.1
      Conserved Domains (3) summary
      cd04047
      Location:170 → 281
      C2B_Copine; C2 domain second repeat in Copine
      cd04048
      Location:36 → 157
      C2A_Copine; C2 domain first repeat in Copine
      cl00057
      Location:291 → 489
      vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...

    3. XM_024991935.2 → XP_024847703.1  copine-8 isoform X3

      Conserved Domains (1) summary
      pfam07002
      Location:1 → 214
      Copine; Copine
    Nucleotide Protein Strain
    Heading Accession and Version

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