These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

1. NM_001075677.2 → NP_001069145.1  hepatocyte growth factor-like protein precursor

   See identical proteins and their annotated locations for NP_001069145.1

   Status: PROVISIONAL

   Source sequence(s)

   BC114002

   UniProtKB/Swiss-Prot

   Q24K22

   UniProtKB/TrEMBL

   E1BDW7

   Related

   ENSBTAP00070048985.1, ENSBTAT00070080832.1

   Conserved Domains (4) summary

   smart00020
   Location:484 → 705

   Tryp_SPc; Trypsin-like serine protease

   smart00130
   Location:369 → 451

   KR; Kringle domain

   cd00190
   Location:485 → 708

   Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...

   pfam00024
   Location:25 → 103

   PAN_1; PAN domain

The following sections contain reference sequences that belong to a specific genome build. Explain

This section includes genomic Reference Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate assemblies. Model RNAs and proteins are also reported here.

Reference ARS-UCD2.0 Primary Assembly

Genomic

1. NC_037349.1 Reference ARS-UCD2.0 Primary Assembly

   Range

   50509855..50514784

   Download

   GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

1. XM_005222804.5 → XP_005222861.1  hepatocyte growth factor-like protein isoform X2

   UniProtKB/TrEMBL

   A0A3Q1LSX3, E1BDW7

   Related

   ENSBTAP00070048994.1, ENSBTAT00070080841.1

   Conserved Domains (4) summary

   smart00020
   Location:497 → 718

   Tryp_SPc; Trypsin-like serine protease

   smart00130
   Location:382 → 464

   KR; Kringle domain

   cd00190
   Location:498 → 721

   Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...

   pfam00024
   Location:39 → 117

   PAN_1; PAN domain

2. XM_005222803.5 → XP_005222860.2  hepatocyte growth factor-like protein isoform X1

   Conserved Domains (5) summary

   smart00130
   Location:122 → 202

   KR; Kringle domain

   cd00190
   Location:527 → 750

   Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...

   cd01099
   Location:37 → 118

   PAN_AP_HGF; Subfamily of PAN/APPLE-like domains; present in N-terminal (N) domains of plasminogen/hepatocyte growth factor proteins, and various proteins found in Bilateria, such as leech anti-platelet proteins. PAN/APPLE domains fulfill diverse biological functions ...

   cl00100
   Location:204 → 244

   KR; Kringle domain; Kringle domains are believed to play a role in binding mediators, such as peptides, other proteins, membranes, or phospholipids. They are autonomous structural domains, found in a varying number of copies, in blood clotting and ...

   cl26464
   Location:234 → 461

   Atrophin-1; Atrophin-1 family

3. XM_059879624.1 → XP_059735607.1  hepatocyte growth factor-like protein isoform X4

   UniProtKB/TrEMBL

   E1BDW7

4. XM_059879623.1 → XP_059735606.1  hepatocyte growth factor-like protein isoform X3

   UniProtKB/TrEMBL

   E1BDW7