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    PARVB parvin beta [ Bos taurus (domestic cattle) ]

    Gene ID: 616294, updated on 30-Jan-2025

    Summary

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    Official Symbol
    PARVBprovided by VGNC
    Official Full Name
    parvin betaprovided by VGNC
    Primary source
    VGNC:VGNC:32590
    See related
    BGD:BT24038; EnsemblRapid:ENSBTAG00070008830
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See PARVB in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 5 NC_037332.1 (114752957..114869668)

    Chromosome 5 - NC_037332.1Genomic Context describing neighboring genes Neighboring gene patatin-like phospholipase domain containing 3 Neighboring gene SAMM50 sorting and assembly machinery component Neighboring gene microRNA mir-11985 Neighboring gene parvin gamma Neighboring gene shisa like 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037332.1 Chromosome 5 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Clone Names

    • MGC143245

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables actin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in actin cytoskeleton organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in establishment or maintenance of cell polarity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in lamellipodium assembly IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in substrate adhesion-dependent cell spreading IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in actin cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in focal adhesion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in lamellipodium IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    beta-parvin

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001102299.1 → NP_001095769.1  beta-parvin

      See identical proteins and their annotated locations for NP_001095769.1

      Status: PROVISIONAL

      Source sequence(s)
      BC148050
      UniProtKB/TrEMBL
      A0A3Q1LPM9, A6QLQ6
      Related
      ENSBTAP00070011822.1, ENSBTAT00070019927.1
      Conserved Domains (1) summary
      pfam00307
      Location:256 → 357
      CH; Calponin homology (CH) domain

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037332.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      114752957..114869668
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_059886738.1 → XP_059742721.1  beta-parvin isoform X4

      UniProtKB/TrEMBL
      A0A3Q1M7B6
      Related
      ENSBTAP00070011835.1, ENSBTAT00070019950.1

    2. XM_024992209.2 → XP_024847977.1  beta-parvin isoform X1

      UniProtKB/TrEMBL
      A0A3Q1M7B6
      Conserved Domains (1) summary
      pfam00307
      Location:79 → 187
      CH; Calponin homology (CH) domain

    3. XM_024992210.2 → XP_024847978.1  beta-parvin isoform X3

      UniProtKB/TrEMBL
      A0A3Q1M7B6, A0AAA9T2D2
      Related
      ENSBTAP00070011813.1, ENSBTAT00070019913.1
      Conserved Domains (1) summary
      pfam00307
      Location:50 → 158
      CH; Calponin homology (CH) domain

    4. XM_024992211.2 → XP_024847979.1  beta-parvin isoform X2

      UniProtKB/TrEMBL
      A0A3Q1M7B6, A0AAA9T2D2
      Conserved Domains (1) summary
      pfam00307
      Location:50 → 158
      CH; Calponin homology (CH) domain
    Nucleotide Protein Strain
    Heading Accession and Version

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