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    TRPC2 transient receptor potential channel 2 [ Bos taurus (domestic cattle) ]

    Gene ID: 282101, updated on 29-Jan-2025

    Summary

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    Official Symbol
    TRPC2provided by VGNC
    Official Full Name
    transient receptor potential channel 2provided by VGNC
    Primary source
    VGNC:VGNC:108921
    See related
    BGD:BT18430; Ensembl:ENSBTAG00000011549
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
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    Genomic context

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    See TRPC2 in Genome Data Viewer
    Location:
    chromosome: 15
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 15 NC_037342.1 (51515258..51532586, complement)

    Chromosome 15 - NC_037342.1Genomic Context describing neighboring genes Neighboring gene ecto-ADP-ribosyltransferase 5-like Neighboring gene ecto-ADP-ribosyltransferase 5-like Neighboring gene XRCC1 N-terminal domain containing 1 Neighboring gene microRNA mir-2317 Neighboring gene ring finger protein 121

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037342.1 Chromosome 15 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. Structure and mRNA expression of a bovine trp homologue related to mammalian trp2 transcripts. Wissenbach U, et al. FEBS Lett, 1998 Jun 5. PMID 9657384
    2. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables inositol 1,4,5 trisphosphate binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables store-operated calcium channel activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in calcium ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of cytosolic calcium ion concentration IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in single fertilization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of cation channel complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    short transient receptor potential channel 2 homolog
    Names
    TRP-2
    bTrp2
    transient receptor protein 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001374468.1 → NP_001361397.1  short transient receptor potential channel 2 homolog

      Status: VALIDATED

      Source sequence(s)
      NKLS02000015
      UniProtKB/TrEMBL
      E1BMQ7
      Related
      ENSBTAP00070042203.1, ENSBTAT00070069231.1
      Conserved Domains (2) summary
      TIGR00870
      Location:63 → 760
      trp; transient-receptor-potential calcium channel protein
      sd00045
      Location:93 → 131
      ANK; ANK repeat [structural motif]

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037342.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      51515258..51532586 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_174477.4: Suppressed sequence

      Description
      NM_174477.4: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O62826.1 GenPept UniProtKB/Swiss-Prot:O62826

    Gene LinkOut

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    Research Materials