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    LRRC4B leucine rich repeat containing 4B [ Bos taurus (domestic cattle) ]

    Gene ID: 539607, updated on 27-Dec-2024

    Summary

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    Official Symbol
    LRRC4Bprovided by VGNC
    Official Full Name
    leucine rich repeat containing 4Bprovided by VGNC
    Primary source
    VGNC:VGNC:31019
    See related
    BGD:BT29834
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See LRRC4B in Genome Data Viewer
    Location:
    chromosome: 18
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 18 NC_037345.1 (56644802..56669238, complement)

    Chromosome 18 - NC_037345.1Genomic Context describing neighboring genes Neighboring gene Josephin domain containing 2 Neighboring gene aspartate dehydrogenase domain containing Neighboring gene uncharacterized LOC132342719 Neighboring gene synaptotagmin 3

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037345.1 Chromosome 18 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables signaling receptor binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in positive regulation of synapse assembly IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of postsynaptic density assembly IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of presynapse assembly IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in synaptic membrane adhesion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in glutamatergic synapse IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in postsynaptic density membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    leucine-rich repeat-containing protein 4B

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001192281.2 → NP_001179210.1  leucine-rich repeat-containing protein 4B precursor

      See identical proteins and their annotated locations for NP_001179210.1

      Status: PROVISIONAL

      Source sequence(s)
      DV889920, NKLS02000018
      UniProtKB/TrEMBL
      E1BPK8
      Conserved Domains (8) summary
      smart00369
      Location:276 → 297
      LRR_TYP; Leucine-rich repeats, typical (most populated) subfamily
      smart00082
      Location:311 → 361
      LRRCT; Leucine rich repeat C-terminal domain
      cd00116
      Location:49 → 217
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
      pfam07679
      Location:364 → 453
      I-set; Immunoglobulin I-set domain
      sd00033
      Location:88 → 111
      LRR_RI; leucine-rich repeat [structural motif]
      pfam12799
      Location:208 → 246
      LRR_4; Leucine Rich repeats (2 copies)
      pfam13855
      Location:87 → 146
      LRR_8; Leucine rich repeat
      cl11960
      Location:378 → 453
      Ig; Immunoglobulin domain

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037345.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      56644802..56669238 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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