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    KLHDC8B kelch domain containing 8B [ Bos taurus (domestic cattle) ]

    Gene ID: 527321, updated on 29-Jan-2025

    Summary

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    Official Symbol
    KLHDC8Bprovided by VGNC
    Official Full Name
    kelch domain containing 8Bprovided by VGNC
    Primary source
    VGNC:VGNC:30640
    See related
    BGD:BT27518; Ensembl:ENSBTAG00000000981
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See KLHDC8B in Genome Data Viewer
    Location:
    chromosome: 22
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 22 NC_037349.1 (50843123..50863720, complement)

    Chromosome 22 - NC_037349.1Genomic Context describing neighboring genes Neighboring gene chromosome 22 C3orf62 homolog Neighboring gene interactor of HORMAD1 1 Neighboring gene chromosome 22 C3orf84 homolog Neighboring gene coiled-coil domain containing 71 Neighboring gene laminin subunit beta-2 Neighboring gene laminin subunit beta-2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037349.1 Chromosome 22 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. Sequence evaluation of four pooled-tissue normalized bovine cDNA libraries and construction of a gene index for cattle. Smith TP, et al. Genome Res, 2001 Apr. PMID 11282978, Free PMC Article
    2. Characterization of 954 bovine full-CDS cDNA sequences. Harhay GP, et al. BMC Genomics, 2005 Nov 23. PMID 16305752, Free PMC Article
    3. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC142469

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in mitotic cytokinetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in mitotic nuclear division IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in nuclear chromosome segregation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cellularization cleavage furrow IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in intercellular bridge IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in midbody IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    kelch domain-containing protein 8B

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001035370.2 → NP_001030447.2  kelch domain-containing protein 8B

      See identical proteins and their annotated locations for NP_001030447.2

      Status: PROVISIONAL

      Source sequence(s)
      BT020815
      UniProtKB/Swiss-Prot
      Q0V8C3, Q5E9V5
      Related
      ENSBTAP00070049327.1, ENSBTAT00070081327.1
      Conserved Domains (5) summary
      smart00612
      Location:176 → 222
      Kelch; Kelch domain
      PRK14131
      Location:1 → 288
      PRK14131; N-acetylneuraminic acid mutarotase; Provisional
      sd00038
      Location:69 → 113
      Kelch; KELCH repeat [structural motif]
      pfam01344
      Location:68 → 114
      Kelch_1; Kelch motif
      pfam13964
      Location:271 → 319
      Kelch_6; Kelch motif

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037349.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      50843123..50863720 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_059879697.1 → XP_059735680.1  kelch domain-containing protein 8B isoform X2

    2. XM_015459584.3 → XP_015315070.1  kelch domain-containing protein 8B isoform X1

      Conserved Domains (2) summary
      sd00038
      Location:69 → 113
      Kelch; KELCH repeat [structural motif]
      cl28614
      Location:7 → 210
      BTB; Broad-Complex, Tramtrack and Bric a brac

    RNA

    1. XR_009492279.1 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5E9V5.1 GenPept UniProtKB/Swiss-Prot:Q5E9V5

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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    Research Materials