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    PLXNB2 plexin B2 [ Bos taurus (domestic cattle) ]

    Gene ID: 508175, updated on 30-Jan-2025

    Summary

    Official Symbol
    PLXNB2provided by VGNC
    Official Full Name
    plexin B2provided by VGNC
    Primary source
    VGNC:VGNC:33062
    See related
    BGD:BT26705; EnsemblRapid:ENSBTAG00070007206
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See PLXNB2 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    40
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 5 NC_037332.1 (119638594..119666305, complement)

    Chromosome 5 - NC_037332.1Genomic Context describing neighboring genes Neighboring gene mitogen-activated protein kinase 12 Neighboring gene mitogen-activated protein kinase 11 Neighboring gene DENN domain containing 6B Neighboring gene protein phosphatase 6 regulatory subunit 2 Neighboring gene SET binding factor 1

    Genomic regions, transcripts, and products

    Genomic Sequence:
    NC_037332.1 Chromosome 5 Reference ARS-UCD2.0 Primary Assembly

    Expression

    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    General gene information

    Markers

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    enables semaphorin receptor activity IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in regulation of cell migration IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    involved_in semaphorin-plexin signaling pathway involved in axon guidance IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    part_of semaphorin receptor complex IEA
    Inferred from Electronic Annotation
    more info
    PubMed 

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001205629.1NP_001192558.1  plexin-B2 precursor

      See identical proteins and their annotated locations for NP_001192558.1

      Status: PROVISIONAL

      Source sequence(s)
      NKLS02000005
      UniProtKB/TrEMBL
      A0A3Q1MQ74
      Related
      ENSBTAP00070009346.1, ENSBTAT00070016302.1
      Conserved Domains (6) summary
      cd01179
      Location:900986
      IPT_plexin_repeat2; Second repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...
      cd01180
      Location:808899
      IPT_plexin_repeat1; First repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...
      pfam01437
      Location:471519
      PSI; Plexin repeat
      pfam08337
      Location:12761810
      Plexin_cytopl; Plexin cytoplasmic RasGAP domain
      cl15674
      Location:9881098
      IPT; Immunoglobulin-like fold, Plexins, Transcription factors (IPT). IPTs are also known as Transcription factor ImmunoGlobin (TIG) domains. They are present in intracellular transcription factors, cell surface receptors (such as plexins and scatter factor ...
      cl15693
      Location:27469
      Sema; The Sema domain, a protein interacting module, of semaphorins and plexins

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037332.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      119638594..119666305 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024991527.2XP_024847295.1  plexin-B2 isoform X2

      UniProtKB/TrEMBL
      A0A3Q1MQ74
      Conserved Domains (6) summary
      cd01179
      Location:900986
      IPT_plexin_repeat2; Second repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...
      cd01180
      Location:808899
      IPT_plexin_repeat1; First repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...
      pfam01437
      Location:471519
      PSI; Plexin repeat
      pfam08337
      Location:12761810
      Plexin_cytopl; Plexin cytoplasmic RasGAP domain
      cl15674
      Location:9881098
      IPT; Immunoglobulin-like fold, Plexins, Transcription factors (IPT). IPTs are also known as Transcription factor ImmunoGlobin (TIG) domains. They are present in intracellular transcription factors, cell surface receptors (such as plexins and scatter factor ...
      cl15693
      Location:27469
      Sema; The Sema domain, a protein interacting module, of semaphorins and plexins
    2. XM_059886231.1XP_059742214.1  plexin-B2 isoform X2

      UniProtKB/TrEMBL
      A0A3Q1MQ74
    3. XM_024991528.2XP_024847296.1  plexin-B2 isoform X2

      UniProtKB/TrEMBL
      A0A3Q1MQ74
      Conserved Domains (6) summary
      cd01179
      Location:900986
      IPT_plexin_repeat2; Second repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...
      cd01180
      Location:808899
      IPT_plexin_repeat1; First repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...
      pfam01437
      Location:471519
      PSI; Plexin repeat
      pfam08337
      Location:12761810
      Plexin_cytopl; Plexin cytoplasmic RasGAP domain
      cl15674
      Location:9881098
      IPT; Immunoglobulin-like fold, Plexins, Transcription factors (IPT). IPTs are also known as Transcription factor ImmunoGlobin (TIG) domains. They are present in intracellular transcription factors, cell surface receptors (such as plexins and scatter factor ...
      cl15693
      Location:27469
      Sema; The Sema domain, a protein interacting module, of semaphorins and plexins
    4. XM_059886233.1XP_059742216.1  plexin-B2 isoform X2

      UniProtKB/TrEMBL
      A0A3Q1MQ74
    5. XM_005207506.5XP_005207563.1  plexin-B2 isoform X2

      See identical proteins and their annotated locations for XP_005207563.1

      UniProtKB/TrEMBL
      A0A3Q1MQ74
      Conserved Domains (6) summary
      cd01179
      Location:900986
      IPT_plexin_repeat2; Second repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...
      cd01180
      Location:808899
      IPT_plexin_repeat1; First repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...
      pfam01437
      Location:471519
      PSI; Plexin repeat
      pfam08337
      Location:12761810
      Plexin_cytopl; Plexin cytoplasmic RasGAP domain
      cl15674
      Location:9881098
      IPT; Immunoglobulin-like fold, Plexins, Transcription factors (IPT). IPTs are also known as Transcription factor ImmunoGlobin (TIG) domains. They are present in intracellular transcription factors, cell surface receptors (such as plexins and scatter factor ...
      cl15693
      Location:27469
      Sema; The Sema domain, a protein interacting module, of semaphorins and plexins
    6. XM_059886232.1XP_059742215.1  plexin-B2 isoform X2

      UniProtKB/TrEMBL
      A0A3Q1MQ74
    7. XM_059886229.1XP_059742212.1  plexin-B2 isoform X1

      UniProtKB/TrEMBL
      A0A3Q1MQ74
    8. XM_005207504.5XP_005207561.2  plexin-B2 isoform X2

      See identical proteins and their annotated locations for XP_005207561.2

      UniProtKB/TrEMBL
      A0A3Q1MQ74
      Conserved Domains (6) summary
      cd01179
      Location:900986
      IPT_plexin_repeat2; Second repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...
      cd01180
      Location:808899
      IPT_plexin_repeat1; First repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...
      pfam01437
      Location:471519
      PSI; Plexin repeat
      pfam08337
      Location:12761810
      Plexin_cytopl; Plexin cytoplasmic RasGAP domain
      cl15674
      Location:9881098
      IPT; Immunoglobulin-like fold, Plexins, Transcription factors (IPT). IPTs are also known as Transcription factor ImmunoGlobin (TIG) domains. They are present in intracellular transcription factors, cell surface receptors (such as plexins and scatter factor ...
      cl15693
      Location:27469
      Sema; The Sema domain, a protein interacting module, of semaphorins and plexins