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    MCM7 minichromosome maintenance complex component 7 [ Bos taurus (domestic cattle) ]

    Gene ID: 539924, updated on 27-Dec-2024

    Summary

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    Official Symbol
    MCM7provided by VGNC
    Official Full Name
    minichromosome maintenance complex component 7provided by VGNC
    Primary source
    VGNC:VGNC:31313
    See related
    BGD:BT16651; Ensembl:ENSBTAG00000030965
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See MCM7 in Genome Data Viewer
    Location:
    chromosome: 25
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 25 NC_037352.1 (36349409..36356836)

    Chromosome 25 - NC_037352.1Genomic Context describing neighboring genes Neighboring gene canopy FGF signaling regulator 4 Neighboring gene TATA-box binding protein associated factor 6 Neighboring gene adaptor related protein complex 4 subunit mu 1 Neighboring gene microRNA mir-106b Neighboring gene microRNA mir-93 Neighboring gene microRNA mir-25 Neighboring gene COP9 signalosome subunit 6 Neighboring gene zinc finger protein 3

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037352.1 Chromosome 25 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables single-stranded DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables single-stranded DNA helicase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in DNA replication IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in DNA replication initiation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in DNA strand elongation involved in DNA replication IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in DNA unwinding involved in DNA replication IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in double-strand break repair via break-induced replication IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of MCM complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    DNA replication licensing factor MCM7
    Names
    MCM7 minichromosome maintenance deficient 7
    minichromosome maintenance protein 7
    NP_001020516.2
    XP_005225242.1
    XP_005225243.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001025345.2 → NP_001020516.2  DNA replication licensing factor MCM7

      See identical proteins and their annotated locations for NP_001020516.2

      Status: PROVISIONAL

      Source sequence(s)
      BC103287
      UniProtKB/Swiss-Prot
      Q3ZBH9
      UniProtKB/TrEMBL
      A0A3Q1MD98
      Related
      ENSBTAP00000003728.4, ENSBTAT00000003728.5
      Conserved Domains (3) summary
      smart00350
      Location:145 → 641
      MCM; minichromosome maintenance proteins
      pfam14551
      Location:12 → 165
      MCM_N; MCM N-terminal domain
      cl21455
      Location:376 → 515
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037352.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      36349409..36356836
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005225185.5 → XP_005225242.1  DNA replication licensing factor MCM7 isoform X1

      See identical proteins and their annotated locations for XP_005225242.1

      UniProtKB/TrEMBL
      A0A3Q1MD98
      Conserved Domains (3) summary
      smart00350
      Location:98 → 594
      MCM; minichromosome maintenance proteins
      pfam14551
      Location:1 → 118
      MCM_N; MCM N-terminal domain
      cl21455
      Location:329 → 468
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

    2. XM_005225186.5 → XP_005225243.1  DNA replication licensing factor MCM7 isoform X1

      See identical proteins and their annotated locations for XP_005225243.1

      UniProtKB/TrEMBL
      A0A3Q1MD98
      Conserved Domains (3) summary
      smart00350
      Location:98 → 594
      MCM; minichromosome maintenance proteins
      pfam14551
      Location:1 → 118
      MCM_N; MCM N-terminal domain
      cl21455
      Location:329 → 468
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q3ZBH9.1 GenPept UniProtKB/Swiss-Prot:Q3ZBH9

    Gene LinkOut

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