CARD11 caspase recruitment domain family member 11 [Bos taurus (domestic cattle)] - Gene

Summary

Official Symbol: CARD11provided by VGNC
Official Full Name: caspase recruitment domain family member 11provided by VGNC
Primary source: VGNC:VGNC:26761
See related: BGD:BT22436; Ensembl:ENSBTAG00000014698
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Bos taurus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs: human mouse all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: chromosome: 25

Exon count:: 28

Annotation release	Status	Assembly	Chr	Location
RS_2024_12	current	ARS-UCD2.0 (GCF_002263795.3)	25	NC_037352.1 (40415994..40523004)

Chromosome 25 - NC_037352.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:: NC_037352.1 Chromosome 25 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help

See details

Project title: Dominette sequence data
BioProject: PRJNA294306
Analysis date: Tue Dec 17 08:57:05 2024

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables CARD domain binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in positive regulation of canonical NF-kappaB signal transduction	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of apoptotic process	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

Go to the top of the page Help

Preferred Names: caspase recruitment domain-containing protein 11

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001109796.2 → NP_001103266.1 caspase recruitment domain-containing protein 11

See identical proteins and their annotated locations for NP_001103266.1

Status: PROVISIONAL

Source sequence(s)

BC153839

UniProtKB/TrEMBL

A0A3Q1M3P1, A8E646, F1MQU2

Conserved Domains (6) summary

cd00992
Location:672 → 744

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

cd08808
Location:15 → 100

CARD_CARD11_CARMA1; Caspase activation and recruitment domain of CARD11-like proteins

pfam15743
Location:295 → 430

SPATA1_C; Spermatogenesis-associated C-terminus

cl17036
Location:769 → 831

SH3; Src Homology 3 domain superfamily

cl17182
Location:161 → 288

NAT_SF; N-Acyltransferase superfamily: Various enyzmes that characteristicly catalyze the transfer of an acyl group to a substrate

cl17190
Location:1001 → 1135

NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

NC_037352.1 Reference ARS-UCD2.0 Primary Assembly

Range

40415994..40523004

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_005225108.5 → XP_005225165.1 caspase recruitment domain-containing protein 11 isoform X2

UniProtKB/TrEMBL

A0A3Q1M3P1

Conserved Domains (5) summary

cd00992
Location:679 → 751

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

cd08808
Location:22 → 107

CARD_CARD11_CARMA1; Caspase activation and recruitment domain of CARD11-like proteins

cl17036
Location:776 → 838

SH3; Src Homology 3 domain superfamily

cl17190
Location:1008 → 1142

NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...

cl25732
Location:143 → 460

SMC_N; RecF/RecN/SMC N terminal domain
XM_005225109.5 → XP_005225166.1 caspase recruitment domain-containing protein 11 isoform X3

UniProtKB/TrEMBL

A0A3Q1M3P1, A0A3S5ZPB2

Related

ENSBTAP00000036945.6, ENSBTAT00000037106.6

Conserved Domains (6) summary

cd00992
Location:673 → 745

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

cd08808
Location:15 → 100

CARD_CARD11_CARMA1; Caspase activation and recruitment domain of CARD11-like proteins

pfam15743
Location:295 → 430

SPATA1_C; Spermatogenesis-associated C-terminus

cl17036
Location:770 → 832

SH3; Src Homology 3 domain superfamily

cl17182
Location:161 → 288

NAT_SF; N-Acyltransferase superfamily: Various enyzmes that characteristicly catalyze the transfer of an acyl group to a substrate

cl17190
Location:1002 → 1136

NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...
XM_005225104.5 → XP_005225161.1 caspase recruitment domain-containing protein 11 isoform X1

See identical proteins and their annotated locations for XP_005225161.1

UniProtKB/TrEMBL

A0A3Q1M3P1

Conserved Domains (5) summary

cd00992
Location:680 → 752

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

cd08808
Location:22 → 107

CARD_CARD11_CARMA1; Caspase activation and recruitment domain of CARD11-like proteins

cl17036
Location:777 → 839

SH3; Src Homology 3 domain superfamily

cl17190
Location:1009 → 1143

NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...

cl25732
Location:143 → 460

SMC_N; RecF/RecN/SMC N terminal domain
XM_015460447.3 → XP_015315933.1 caspase recruitment domain-containing protein 11 isoform X1

UniProtKB/TrEMBL

A0A3Q1M3P1

Conserved Domains (5) summary

cd00992
Location:680 → 752

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

cd08808
Location:22 → 107

CARD_CARD11_CARMA1; Caspase activation and recruitment domain of CARD11-like proteins

cl17036
Location:777 → 839

SH3; Src Homology 3 domain superfamily

cl17190
Location:1009 → 1143

NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...

cl25732
Location:143 → 460

SMC_N; RecF/RecN/SMC N terminal domain
XM_005225105.5 → XP_005225162.1 caspase recruitment domain-containing protein 11 isoform X1

See identical proteins and their annotated locations for XP_005225162.1

UniProtKB/TrEMBL

A0A3Q1M3P1

Conserved Domains (5) summary

cd00992
Location:680 → 752

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

cd08808
Location:22 → 107

CARD_CARD11_CARMA1; Caspase activation and recruitment domain of CARD11-like proteins

cl17036
Location:777 → 839

SH3; Src Homology 3 domain superfamily

cl17190
Location:1009 → 1143

NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...

cl25732
Location:143 → 460

SMC_N; RecF/RecN/SMC N terminal domain
XM_059881294.1 → XP_059737277.1 caspase recruitment domain-containing protein 11 isoform X1

UniProtKB/TrEMBL

A0A3Q1M3P1
XM_005225106.5 → XP_005225163.1 caspase recruitment domain-containing protein 11 isoform X1

See identical proteins and their annotated locations for XP_005225163.1

UniProtKB/TrEMBL

A0A3Q1M3P1

Related

ENSBTAP00000064393.2, ENSBTAT00000081933.2

Conserved Domains (5) summary

cd00992
Location:680 → 752

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

cd08808
Location:22 → 107

CARD_CARD11_CARMA1; Caspase activation and recruitment domain of CARD11-like proteins

cl17036
Location:777 → 839

SH3; Src Homology 3 domain superfamily

cl17190
Location:1009 → 1143

NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...

cl25732
Location:143 → 460

SMC_N; RecF/RecN/SMC N terminal domain