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    SBF1 SET binding factor 1 [ Bos taurus (domestic cattle) ]

    Gene ID: 510349, updated on 30-Jan-2025

    Summary

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    Official Symbol
    SBF1provided by VGNC
    Official Full Name
    SET binding factor 1provided by VGNC
    Primary source
    VGNC:VGNC:34305
    See related
    BGD:BT18409; EnsemblRapid:ENSBTAG00070007303
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See SBF1 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    41
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 5 NC_037332.1 (119751853..119784060, complement)

    Chromosome 5 - NC_037332.1Genomic Context describing neighboring genes Neighboring gene plexin B2 Neighboring gene DENN domain containing 6B Neighboring gene protein phosphatase 6 regulatory subunit 2 Neighboring gene basic proline-rich protein Neighboring gene uncharacterized LOC101903087 Neighboring gene adrenomedullin 2 Neighboring gene myo-inositol oxygenase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037332.1 Chromosome 5 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables guanyl-nucleotide exchange factor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    myotubularin-related protein 5

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037332.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      119751853..119784060 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024992879.2 → XP_024848647.1  myotubularin-related protein 5 isoform X4

      UniProtKB/TrEMBL
      A0A3Q1MFD4, G5E5Q8
      Related
      ENSBTAP00070009552.1, ENSBTAT00070016548.1
      Conserved Domains (7) summary
      smart00801
      Location:364 → 432
      dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
      smart00799
      Location:129 → 310
      DENN; Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN
      smart00800
      Location:1 → 86
      uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins
      cd01235
      Location:1756 → 1861
      PH_Sbf1_hMTMR5; Set binding factor 1 (also called Human MTMR5) Pleckstrin Homology (PH) domain
      pfam06602
      Location:1127 → 1527
      Myotub-related; Myotubularin-like phosphatase domain
      pfam12335
      Location:543 → 763
      SBF2; Myotubularin protein
      cl17171
      Location:892 → 1010
      PH-like; Pleckstrin homology-like domain

    2. XM_024992877.2 → XP_024848645.1  myotubularin-related protein 5 isoform X2

      UniProtKB/TrEMBL
      A0A3Q1M4Y7, A0A3Q1MFD4
      Related
      ENSBTAP00070009543.1, ENSBTAT00070016539.1
      Conserved Domains (7) summary
      smart00801
      Location:364 → 432
      dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
      smart00799
      Location:129 → 310
      DENN; Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN
      smart00800
      Location:1 → 86
      uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins
      cd01235
      Location:1782 → 1887
      PH_Sbf1_hMTMR5; Set binding factor 1 (also called Human MTMR5) Pleckstrin Homology (PH) domain
      pfam06602
      Location:1127 → 1553
      Myotub-related; Myotubularin-like phosphatase domain
      pfam12335
      Location:543 → 763
      SBF2; Myotubularin protein
      cl17171
      Location:892 → 1010
      PH-like; Pleckstrin homology-like domain

    3. XM_024992878.2 → XP_024848646.1  myotubularin-related protein 5 isoform X3

      UniProtKB/TrEMBL
      A0A3Q1MFD4
      Conserved Domains (7) summary
      smart00801
      Location:364 → 432
      dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
      smart00799
      Location:129 → 310
      DENN; Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN
      smart00800
      Location:1 → 86
      uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins
      cd01235
      Location:1779 → 1884
      PH_Sbf1_hMTMR5; Set binding factor 1 (also called Human MTMR5) Pleckstrin Homology (PH) domain
      pfam06602
      Location:1150 → 1550
      Myotub-related; Myotubularin-like phosphatase domain
      pfam12335
      Location:543 → 786
      SBF2; Myotubularin protein
      cl17171
      Location:915 → 1033
      PH-like; Pleckstrin homology-like domain

    4. XM_024992875.2 → XP_024848643.1  myotubularin-related protein 5 isoform X1

      UniProtKB/TrEMBL
      A0A3Q1MFD4
      Conserved Domains (7) summary
      smart00801
      Location:364 → 432
      dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
      smart00799
      Location:129 → 310
      DENN; Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN
      smart00800
      Location:1 → 86
      uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins
      cd01235
      Location:1805 → 1910
      PH_Sbf1_hMTMR5; Set binding factor 1 (also called Human MTMR5) Pleckstrin Homology (PH) domain
      pfam06602
      Location:1150 → 1576
      Myotub-related; Myotubularin-like phosphatase domain
      pfam12335
      Location:543 → 786
      SBF2; Myotubularin protein
      cl17171
      Location:915 → 1033
      PH-like; Pleckstrin homology-like domain
    Nucleotide Protein Strain
    Heading Accession and Version

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