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    Arl10 ARF like GTPase 10 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 306767, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Arl10provided by RGD
    Official Full Name
    ARF like GTPase 10provided by RGD
    Primary source
    RGD:1303298
    See related
    EnsemblRapid:ENSRNOG00000045948 AllianceGenome:RGD:1303298
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable GTP binding activity and GTPase activity. Predicted to be located in mitochondrion. Orthologous to human ARL10 (ADP ribosylation factor like GTPase 10). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Brain (RPKM 52.7), Lung (RPKM 45.2) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Arl10 in Genome Data Viewer
    Location:
    17p14
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 17 NC_086035.1 (10035320..10043732, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 17 NC_051352.1 (10030213..10038625, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 17 NC_005116.4 (10567064..10575518, complement)

    Chromosome 17 - NC_086035.1Genomic Context describing neighboring genes Neighboring gene HIG1 hypoxia inducible domain family, member 2A Neighboring gene NOP16 nucleolar protein Neighboring gene KIAA1191 homolog Neighboring gene SUMO-interacting motifs containing 1 Neighboring gene uncharacterized LOC134482678 Neighboring gene uncharacterized LOC134482679

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. RASL11A, member of a novel small monomeric GTPase gene family, is down-regulated in prostate tumors. Louro R, et al. Biochem Biophys Res Commun, 2004 Apr 9. PMID 15033445
    2. Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context. Morgenstern M, et al. Cell Metab, 2021 Dec 7. PMID 34800366, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables GTP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ADP-ribosylation factor-like protein 10
    Names
    ADP-ribosylation factor like GTPase 10
    ADP-ribosylation factor-like 10

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001399321.1 → NP_001386250.1  ADP-ribosylation factor-like protein 10 isoform 1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000017
      UniProtKB/TrEMBL
      A6KAY8
      Related
      ENSRNOP00000095832.1, ENSRNOT00000108677.2
      Conserved Domains (1) summary
      cl38936
      Location:78 → 236
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

    2. NM_207165.2 → NP_997048.1  ADP-ribosylation factor-like protein 10 isoform 2

      See identical proteins and their annotated locations for NP_997048.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000017
      UniProtKB/TrEMBL
      A6KAY9, M0RBH4, Q6IMA8
      Related
      ENSRNOP00000066910.1, ENSRNOT00000073186.4
      Conserved Domains (1) summary
      cl21455
      Location:28 → 186
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086035.1 Reference GRCr8

      Range
      10035320..10043732 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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