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    Rbm41 RNA binding motif protein 41 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 680581, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Rbm41provided by RGD
    Official Full Name
    RNA binding motif protein 41provided by RGD
    Primary source
    RGD:1590579
    See related
    EnsemblRapid:ENSRNOG00000057622 AllianceGenome:RGD:1590579
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable U12 snRNA binding activity and pre-mRNA intronic binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be part of U12-type spliceosomal complex. Orthologous to human RBM41 (RNA binding motif protein 41). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Thymus (RPKM 52.0), Lung (RPKM 47.2) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Rbm41 in Genome Data Viewer
    Location:
    Xq32
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) X NC_086039.1 (108394323..108448969, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) X NC_051356.1 (103605732..103660381, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) X NC_005120.4 (111272347..111325203, complement)

    Chromosome X - NC_086039.1Genomic Context describing neighboring genes Neighboring gene NMD3 ribosome export adaptor, pseudogene 1 Neighboring gene protein kinase C and casein kinase substrate in neurons 2, pseudogene 1 Neighboring gene nucleoporin 62 C-terminal like Neighboring gene dynein axonemal assembly factor 6 Neighboring gene small nucleolar RNA SNORA48

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables U12 snRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables pre-mRNA intronic binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in mRNA splicing, via spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of U12-type spliceosomal complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    RNA-binding protein 41

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001109420.1 → NP_001102890.1  RNA-binding protein 41

      See identical proteins and their annotated locations for NP_001102890.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000021
      UniProtKB/TrEMBL
      A6HLS4, A6HLS5, D3ZTA4
      Related
      ENSRNOP00000069686.1, ENSRNOT00000086785.3
      Conserved Domains (2) summary
      COG0724
      Location:300 → 391
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      cd12239
      Location:308 → 385
      RRM2_RBM40_like; RNA recognition motif 2 in RNA-binding protein 40 (RBM40) and similar proteins

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086039.1 Reference GRCr8

      Range
      108394323..108448969 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039100061.1 → XP_038955989.1  RNA-binding protein 41 isoform X1

      Conserved Domains (2) summary
      TIGR01622
      Location:45 → 344
      SF-CC1; splicing factor, CC1-like family
      cd12239
      Location:254 → 331
      RRM2_RBM40_like; RNA recognition motif 2 (RRM2) found in RNA-binding protein 40 (RBM40) and similar proteins

    2. XM_063280300.1 → XP_063136370.1  RNA-binding protein 41 isoform X2

    RNA

    1. XR_010061244.1 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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