LINC01614 long intergenic non-protein coding RNA 1614 [Homo sapiens (human)] - Gene

Summary

Official Symbol: LINC01614provided by HGNC
Official Full Name: long intergenic non-protein coding RNA 1614provided by HGNC
Primary source: HGNC:HGNC:51847
See related: Ensembl:ENSG00000230838 AllianceGenome:HGNC:51847
Gene type: ncRNA
RefSeq status: VALIDATED
Organism: Homo sapiens
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as: LCAL4
Expression: Low expression observed in reference dataset See more
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Genomic context

Location:: 2q35

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCh38.p14 (GCF_000001405.40)	2	NC_000002.12 (215718043..215720946)
RS_2024_08	current	T2T-CHM13v2.0 (GCF_009914755.1)	2	NC_060926.1 (216203414..216206317)
RS_2024_09	previous assembly	GRCh37.p13 (GCF_000001405.25)	2	NC_000002.11 (216582766..216585669)

Chromosome 2 - NC_000002.12 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Tissue-specific circular RNA induction during human fetal development
Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
BioProject: PRJNA270632
Publication: PMID 26076956
Analysis date: Mon Apr 2 22:54:59 2018

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

LINC01614 activated by SP1 promoted malignant behavior of triple-negative breast cancer cells via the WNT/b-Catenin signaling pathway.
Title: LINC01614 activated by SP1 promoted malignant behavior of triple-negative breast cancer cells via the WNT/b-Catenin signaling pathway.
Long Noncoding RNA LINC01614 is a Diagnostic and Prognostic Marker for Breast Cancer.
Title: Long Noncoding RNA LINC01614 is a Diagnostic and Prognostic Marker for Breast Cancer.
Long noncoding RNA 01614 hyperactivates WNT/betacatenin signaling to promote pancreatic cancer progression by suppressing GSK3beta.
Title: Long non‑coding RNA 01614 hyperactivates WNT/β‑catenin signaling to promote pancreatic cancer progression by suppressing GSK‑3β.
Risk SNP-mediated LINC01614 upregulation drives head and neck squamous cell carcinoma progression via PI3K/AKT signaling pathway.
Title: Risk SNP-mediated LINC01614 upregulation drives head and neck squamous cell carcinoma progression via PI3K/AKT signaling pathway.
LINC01614 promotes osteosarcoma progression via miR-520a-3p/SNX3 axis.
Title: LINC01614 promotes osteosarcoma progression via miR-520a-3p/SNX3 axis.
It was shown that LINC01614 promoted the expression of FOXP1 by inhibiting miR-217, which ultimately stimulated the development of lung adenocarcinoma.
Title: Knockdown of LINC01614 inhibits lung adenocarcinoma cell progression by up-regulating miR-217 and down-regulating FOXP1.

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Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

General gene information

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Other Names

TCONS_00003105
lung cancer associated lncRNA 4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.