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    Zdhhc13 zinc finger, DHHC domain containing 13 [ Mus musculus (house mouse) ]

    Gene ID: 243983, updated on 9-Dec-2024

    Summary

    Official Symbol
    Zdhhc13provided by MGI
    Official Full Name
    zinc finger, DHHC domain containing 13provided by MGI
    Primary source
    MGI:MGI:1919227
    See related
    Ensembl:ENSMUSG00000030471 AllianceGenome:MGI:1919227
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    skc4; kojak; HIP3RP; Hip14l; C530010M18; 2410004E01Rik
    Summary
    Enables magnesium ion transmembrane transporter activity and palmitoyltransferase activity. Predicted to be involved in protein targeting to membrane. Located in Golgi membrane and Golgi-associated vesicle membrane. Is expressed in several structures, including early conceptus; esophagus epithelium; genitourinary system; molar; and sensory organ. Used to study Huntington's disease. Orthologous to human ZDHHC13 (zinc finger DHHC-type palmitoyltransferase 13). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in placenta adult (RPKM 21.6), bladder adult (RPKM 15.1) and 26 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Zdhhc13 in Genome Data Viewer
    Location:
    7 B4; 7 31.11 cM
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (48438751..48477188)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (48788998..48827440)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene predicted gene 45086 Neighboring gene VISTA enhancer mm1586 Neighboring gene predicted gene, 32263 Neighboring gene STARR-positive B cell enhancer ABC_E1734 Neighboring gene STARR-seq mESC enhancer starr_18887 Neighboring gene cysteine and glycine-rich protein 3 Neighboring gene STARR-positive B cell enhancer ABC_E3719 Neighboring gene STARR-positive B cell enhancer ABC_E8174 Neighboring gene E2F transcription factor 8 Neighboring gene predicted gene 2788

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables magnesium ion transmembrane transporter activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables palmitoyltransferase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables protein-cysteine S-palmitoyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in magnesium ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in Golgi apparatus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in Golgi membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in Golgi-associated vesicle membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
     
    located_in endoplasmic reticulum ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    palmitoyltransferase ZDHHC13
    Names
    DHHC-13
    HIP14-related protein
    huntingtin-interacting protein 14-related protein
    probable palmitoyltransferase ZDHHC13
    zinc finger DHHC domain-containing protein 13
    NP_082307.1
    XP_006540959.1
    XP_030098440.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_028031.3NP_082307.1  palmitoyltransferase ZDHHC13

      See identical proteins and their annotated locations for NP_082307.1

      Status: PROVISIONAL

      Source sequence(s)
      AC124977
      Consensus CDS
      CCDS52259.1
      UniProtKB/Swiss-Prot
      Q3UK32, Q3UKV1, Q9CWU2
      Related
      ENSMUSP00000112498.2, ENSMUST00000118927.8
      Conserved Domains (5) summary
      cd00204
      Location:79192
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam01529
      Location:423556
      zf-DHHC; DHHC palmitoyltransferase
      pfam12796
      Location:86179
      Ank_2; Ankyrin repeats (3 copies)
      pfam13857
      Location:202257
      Ank_5; Ankyrin repeats (many copies)
      sd00045
      Location:81112
      ANK; ANK repeat [structural motif]

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      48438751..48477188
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030242580.2XP_030098440.1  palmitoyltransferase ZDHHC13 isoform X1

      UniProtKB/TrEMBL
      D3YY07
      Conserved Domains (4) summary
      COG0666
      Location:15141
      ANKYR; Ankyrin repeat [Signal transduction mechanisms]
      sd00045
      Location:1849
      ANK; ANK repeat [structural motif]
      pfam01529
      Location:293427
      DHHC; DHHC palmitoyltransferase
      cl26595
      Location:151262
      DUF2070; Predicted membrane protein (DUF2070)
    2. XM_006540896.5XP_006540959.1  palmitoyltransferase ZDHHC13 isoform X1

      See identical proteins and their annotated locations for XP_006540959.1

      UniProtKB/TrEMBL
      D3YY07
      Related
      ENSMUSP00000123603.2, ENSMUST00000125280.8
      Conserved Domains (4) summary
      COG0666
      Location:15141
      ANKYR; Ankyrin repeat [Signal transduction mechanisms]
      sd00045
      Location:1849
      ANK; ANK repeat [structural motif]
      pfam01529
      Location:293427
      DHHC; DHHC palmitoyltransferase
      cl26595
      Location:151262
      DUF2070; Predicted membrane protein (DUF2070)