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    Borcs7 BLOC-1 related complex subunit 7 [ Mus musculus (house mouse) ]

    Gene ID: 66439, updated on 27-Nov-2024

    Summary

    Official Symbol
    Borcs7provided by MGI
    Official Full Name
    BLOC-1 related complex subunit 7provided by MGI
    Primary source
    MGI:MGI:1913689
    See related
    Ensembl:ENSMUSG00000062376 AllianceGenome:MGI:1913689
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    2010012O05Rik; 4930569L17Rik
    Summary
    Acts upstream of or within several processes, including lysosome localization; motor behavior; and response to cycloheximide. Is active in lysosome. Used to study hereditary spastic paraplegia and neuroaxonal dystrophy. Orthologous to human BORCS7 (BLOC-1 related complex subunit 7). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Ubiquitous expression in frontal lobe adult (RPKM 5.2), cortex adult (RPKM 4.8) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Borcs7 in Genome Data Viewer
    Location:
    19 C3; 19 38.97 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (46678345..46691821)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (46689906..46703382)

    Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene Cyp17a1 promoter Neighboring gene cytochrome P450, family 17, subfamily a, polypeptide 1 Neighboring gene predicted gene, 41857 Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene Neighboring gene arsenite methyltransferase Neighboring gene STARR-positive B cell enhancer ABC_E8753 Neighboring gene cyclin M2 Neighboring gene STARR-seq mESC enhancer starr_46325 Neighboring gene STARR-seq mESC enhancer starr_46328

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    part_of BORC complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of BORC complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of BORC complex ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in cytoplasmic side of lysosomal membrane NAS
    Non-traceable Author Statement
    more info
    PubMed 
    is_active_in lysosome IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 

    General protein information

    Preferred Names
    BLOC-1-related complex subunit 7
    Names
    UPF0693 protein C10orf32 homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_025563.3NP_079839.1  BLOC-1-related complex subunit 7

      See identical proteins and their annotated locations for NP_079839.1

      Status: VALIDATED

      Source sequence(s)
      AC161865
      Consensus CDS
      CCDS38011.1
      UniProtKB/Swiss-Prot
      Q9CRC6
      Related
      ENSMUSP00000074447.8, ENSMUST00000074912.8
      Conserved Domains (1) summary
      pfam16088
      Location:1103
      BORCS7; BLOC-1-related complex sub-unit 7

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000085.7 Reference GRCm39 C57BL/6J

      Range
      46678345..46691821
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)