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    Rfpl4b ret finger protein-like 4B [ Mus musculus (house mouse) ]

    Gene ID: 215919, updated on 27-Nov-2024

    Summary

    Official Symbol
    Rfpl4bprovided by MGI
    Official Full Name
    ret finger protein-like 4Bprovided by MGI
    Primary source
    MGI:MGI:2684908
    See related
    Ensembl:ENSMUSG00000094311 AllianceGenome:MGI:2684908
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm62; Gm3037; 100040915
    Summary
    Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in innate immune response; positive regulation of type I interferon-mediated signaling pathway; and protein monoubiquitination. Orthologous to human RFPL4B (ret finger protein like 4B). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Low expression observed in reference dataset See more
    Orthologs
    NEW
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    Genomic context

    See Rfpl4b in Genome Data Viewer
    Location:
    10 B1; 10 19.98 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (38696537..38697775, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (38820541..38821779, complement)

    Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 40624 Neighboring gene STARR-seq mESC enhancer starr_26369 Neighboring gene STARR-seq mESC enhancer starr_26371 Neighboring gene STARR-seq mESC enhancer starr_26372 Neighboring gene predicted gene, 22911 Neighboring gene STARR-seq mESC enhancer starr_26375 Neighboring gene STARR-seq mESC enhancer starr_26376 Neighboring gene STARR-seq mESC enhancer starr_26377 Neighboring gene STARR-seq mESC enhancer starr_26378 Neighboring gene predicted gene, 17779 Neighboring gene laminin, alpha 4 Neighboring gene STARR-seq mESC enhancer starr_26379

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General protein information

    Preferred Names
    ret finger protein-like 4B
    Names
    ret finger protein-like 4 pseudogene

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001177783.1NP_001171254.1  ret finger protein-like 4B

      See identical proteins and their annotated locations for NP_001171254.1

      Status: VALIDATED

      Source sequence(s)
      AC153539
      Consensus CDS
      CCDS56699.1
      UniProtKB/TrEMBL
      J3QPR6
      Related
      ENSMUSP00000137446.2, ENSMUST00000179279.2
      Conserved Domains (2) summary
      cd00162
      Location:3075
      RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
      cl02614
      Location:132237
      SPRY; SPRY domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000076.7 Reference GRCm39 C57BL/6J

      Range
      38696537..38697775 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NG_018788.1: Suppressed sequence

      Description
      NG_018788.1: This RefSeq was permanently suppressed because it is now thought that this gene does encode a protein.