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    Commd2 COMM domain containing 2 [ Mus musculus (house mouse) ]

    Gene ID: 52245, updated on 9-Dec-2024

    Summary

    Official Symbol
    Commd2provided by MGI
    Official Full Name
    COMM domain containing 2provided by MGI
    Primary source
    MGI:MGI:1098806
    See related
    Ensembl:ENSMUSG00000036513 AllianceGenome:MGI:1098806
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    HSPC042; D3Ertd176e; 1190017G07Rik
    Summary
    Predicted to be located in cytoplasm. Orthologous to human COMMD2 (COMM domain containing 2). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in CNS E14 (RPKM 6.7), CNS E11.5 (RPKM 6.7) and 28 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Commd2 in Genome Data Viewer
    Location:
    3 D; 3 27.94 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (57551770..57559105, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (57644349..57651684, complement)

    Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene WW domain containing transcription regulator 1 Neighboring gene NEDD8-conjugating enzyme UBE2F pseudogene Neighboring gene STARR-seq mESC enhancer starr_07733 Neighboring gene STARR-seq mESC enhancer starr_07736 Neighboring gene predicted gene, 26671 Neighboring gene microRNA 6377 Neighboring gene predicted gene, 46805 Neighboring gene STARR-positive B cell enhancer ABC_E7913 Neighboring gene STARR-seq mESC enhancer starr_07737 Neighboring gene ankyrin repeat and ubiquitin domain containing 1 Neighboring gene ribosomal protein S11 pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (1) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
     
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
     
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    COMM domain-containing protein 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_175095.4NP_780304.2  COMM domain-containing protein 2

      See identical proteins and their annotated locations for NP_780304.2

      Status: PROVISIONAL

      Source sequence(s)
      AK143821
      Consensus CDS
      CCDS17362.1
      UniProtKB/Swiss-Prot
      Q8BJI3, Q8BXC6
      UniProtKB/TrEMBL
      Q497T6
      Related
      ENSMUSP00000124819.2, ENSMUST00000160959.8
      Conserved Domains (1) summary
      cd04750
      Location:26190
      Commd2; COMM_Domain containing protein 2. The COMM Domain is found at the C-terminus of a variety of proteins; presumably all COMM_Domain containing proteins are located in the nucleus and the COMM domain plays a role in protein-protein interactions. Several ...

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000069.7 Reference GRCm39 C57BL/6J

      Range
      57551770..57559105 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)