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    Ttc22 tetratricopeptide repeat domain 22 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 298300, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Ttc22provided by RGD
    Official Full Name
    tetratricopeptide repeat domain 22provided by RGD
    Primary source
    RGD:1561518
    See related
    EnsemblRapid:ENSRNOG00000007189 AllianceGenome:RGD:1561518
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1561518
    Summary
    Orthologous to human TTC22 (tetratricopeptide repeat domain 22). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Lung (RPKM 25.2), Kidney (RPKM 20.7) and 7 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Ttc22 in Genome Data Viewer
    Location:
    5q34
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 5 NC_086023.1 (126630808..126651954)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 5 NC_051340.1 (121401973..121423130)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 5 NC_005104.4 (126217036..126243178)

    Chromosome 5 - NC_086023.1Genomic Context describing neighboring genes Neighboring gene 24-dehydrocholesterol reductase Neighboring gene uncharacterized LOC120102943 Neighboring gene ciliary microtubule associated protein 2 Neighboring gene uncharacterized LOC120102944 Neighboring gene prolyl-tRNA synthetase 2, mitochondrial Neighboring gene tetratricopeptide repeat domain 4

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Phosphorylation and degradation of tomosyn-2 de-represses insulin secretion. Bhatnagar S, et al. J Biol Chem, 2014 Sep 5. PMID 25002582, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    General protein information

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    Preferred Names
    tetratricopeptide repeat protein 22

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001106671.1 → NP_001100141.1  tetratricopeptide repeat protein 22

      See identical proteins and their annotated locations for NP_001100141.1

      Status: PROVISIONAL

      Source sequence(s)
      CH474008
      UniProtKB/TrEMBL
      A6JYN4, D3ZRX3
      Related
      ENSRNOP00000009582.3, ENSRNOT00000009582.7
      Conserved Domains (1) summary
      sd00006
      Location:65 → 95
      TPR; TPR repeat [structural motif]

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086023.1 Reference GRCr8

      Range
      126630808..126651954
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017593264.3 → XP_017448753.1  tetratricopeptide repeat protein 22 isoform X1

      UniProtKB/TrEMBL
      A6JYN4, D3ZRX3
      Conserved Domains (1) summary
      sd00006
      Location:65 → 95
      TPR; TPR repeat [structural motif]
    Nucleotide Protein Strain
    Heading Accession and Version

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