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    Fbxo39 F-box protein 39 [ Mus musculus (house mouse) ]

    Gene ID: 628100, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Fbxo39provided by MGI
    Official Full Name
    F-box protein 39provided by MGI
    Primary source
    MGI:MGI:3505735
    See related
    Ensembl:ENSMUSG00000070388 AllianceGenome:MGI:3505735
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    1700010H23Rik
    Summary
    Predicted to be involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process. Predicted to be part of SCF ubiquitin ligase complex. Orthologous to human FBXO39 (F-box protein 39). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Restricted expression toward testis adult (RPKM 42.6) See more
    Orthologs
    human all
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    Genomic context

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    See Fbxo39 in Genome Data Viewer
    Location:
    11 B4; 11 44.0 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (72205270..72210245)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (72314444..72319419)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene solute carrier family 13 (sodium-dependent citrate transporter), member 5 Neighboring gene RIKEN cDNA 1700051A21 gene Neighboring gene STARR-seq mESC enhancer starr_29902 Neighboring gene XIAP associated factor 1 Neighboring gene predicted gene, 51867 Neighboring gene tektin 1 Neighboring gene predicted gene, 34317

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Systematic analysis and nomenclature of mammalian F-box proteins. Jin J, et al. Genes Dev, 2004 Nov 1. PMID 15520277, Free PMC Article
    2. USP7 represses lineage differentiation genes in mouse embryonic stem cells by both catalytic and noncatalytic activities. Liu C, et al. Sci Adv, 2023 May 19. PMID 37196079, Free PMC Article
    3. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
    4. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
    5. Functional annotation of a full-length mouse cDNA collection. Kawai J, et al. Nature, 2001 Feb 8. PMID 11217851

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of SCF ubiquitin ligase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    F-box only protein 39
    Names
    F-box protein 38

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001099688.2 → NP_001093158.1  F-box only protein 39

      See identical proteins and their annotated locations for NP_001093158.1

      Status: PROVISIONAL

      Source sequence(s)
      AL929071, AV040000, BU937284, CR519476
      Consensus CDS
      CCDS36214.1
      UniProtKB/Swiss-Prot
      Q5NBU5
      Related
      ENSMUSP00000104144.2, ENSMUST00000108504.2
      Conserved Domains (1) summary
      pfam12937
      Location:16 → 57
      F-box-like

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      72205270..72210245
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006533901.3 → XP_006533964.2  F-box only protein 39 isoform X1

      Conserved Domains (1) summary
      pfam12937
      Location:53 → 94
      F-box-like

    2. XM_006533902.3 → XP_006533965.2  F-box only protein 39 isoform X2

      UniProtKB/Swiss-Prot
      Q5NBU5
      Conserved Domains (1) summary
      pfam12937
      Location:16 → 57
      F-box-like
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5NBU5.2 GenPept UniProtKB/Swiss-Prot:Q5NBU5

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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