Phospho1 phosphoethanolamine/phosphocholine phosphatase 1 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Phospho1provided by RGD
Official Full Name: phosphoethanolamine/phosphocholine phosphatase 1provided by RGD
Primary source: RGD:1306182
See related: EnsemblRapid:ENSRNOG00000005569 AllianceGenome:RGD:1306182
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable phosphocholine phosphatase activity; phosphoethanolamine phosphatase activity; and pyrophosphatase activity. Predicted to be involved in bone mineralization involved in bone maturation. Predicted to act upstream of or within endochondral ossification. Predicted to be located in extracellular matrix. Predicted to be active in extracellular membrane-bounded organelle. Orthologous to human PHOSPHO1 (phosphoethanolamine/phosphocholine phosphatase 1). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Biased expression in Muscle (RPKM 221.7), Heart (RPKM 105.3) and 8 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 10q26

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	10	NC_086028.1 (81258810..81266345)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	10	NC_051345.1 (80762062..80769596)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	10	NC_005109.4 (83635557..83643862)

Chromosome 10 - NC_086028.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Markers

NoName (e-PCR)
- UniSTS:488471

RH133502 (e-PCR)
- UniSTS:216785

AW434650 (e-PCR)
- UniSTS:248790

NoName (e-PCR)
- UniSTS:494068

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables phosphatase activity	IBA Inferred from Biological aspect of Ancestor more info
enables phosphocholine phosphatase activity	ISO Inferred from Sequence Orthology more info
enables phosphoethanolamine phosphatase activity	ISO Inferred from Sequence Orthology more info
enables pyrophosphatase activity	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in bone mineralization	ISO Inferred from Sequence Orthology more info
involved_in bone mineralization involved in bone maturation	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within bone mineralization involved in bone maturation	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within endochondral ossification	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
located_in extracellular matrix	ISO Inferred from Sequence Orthology more info
is_active_in extracellular membrane-bounded organelle	ISO Inferred from Sequence Orthology more info
located_in extracellular membrane-bounded organelle	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: phosphoethanolamine/phosphocholine phosphatase

Names: phosphatase, orphan 1

NP_001099303.1

EC 3.1.3.75

XP_006247246.1

EC 3.1.3.75

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.