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    Ngp neutrophilic granule protein [ Rattus norvegicus (Norway rat) ]

    Gene ID: 301026, updated on 27-Nov-2024

    Summary

    Official Symbol
    Ngpprovided by RGD
    Official Full Name
    neutrophilic granule proteinprovided by RGD
    Primary source
    RGD:1308994
    See related
    EnsemblRapid:ENSRNOG00000024330 AllianceGenome:RGD:1308994
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable cysteine-type endopeptidase inhibitor activity. Predicted to be involved in defense response to bacterium. Predicted to be active in extracellular space. [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Spleen (RPKM 129.6), Thymus (RPKM 37.0) and 1 other tissue See more
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    Genomic context

    See Ngp in Genome Data Viewer
    Location:
    8q32
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (119272605..119275972)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (110394173..110397571)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (118662335..118665699)

    Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene SREBF chaperone Neighboring gene protein tyrosine phosphatase, non-receptor type 23 Neighboring gene kelch-like family member 18 Neighboring gene kinesin family member 9 Neighboring gene SET domain containing 2, histone lysine methyltransferase

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables cysteine-type endopeptidase inhibitor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in defense response to bacterium IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    neutrophilic granule protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001106862.1NP_001100332.1  neutrophilic granule protein precursor

      See identical proteins and their annotated locations for NP_001100332.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473954
      UniProtKB/TrEMBL
      A6I3E3, D3ZY96
      Related
      ENSRNOP00000032468.2, ENSRNOT00000029755.4
      Conserved Domains (1) summary
      pfam00666
      Location:2488
      Cathelicidins; Cathelicidin

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086026.1 Reference GRCr8

      Range
      119272605..119275972
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)