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    Ttc33 tetratricopeptide repeat domain 33 [ Mus musculus (house mouse) ]

    Gene ID: 67515, updated on 9-Dec-2024

    Summary

    Official Symbol
    Ttc33provided by MGI
    Official Full Name
    tetratricopeptide repeat domain 33provided by MGI
    Primary source
    MGI:MGI:1914765
    See related
    Ensembl:ENSMUSG00000022151 AllianceGenome:MGI:1914765
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Osrf; 2410099M07Rik; 2900001O04Rik
    Summary
    Is expressed in central nervous system; dorsal root ganglion; and olfactory epithelium. Orthologous to human TTC33 (tetratricopeptide repeat domain 33). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Broad expression in cerebellum adult (RPKM 11.6), frontal lobe adult (RPKM 10.5) and 22 other tissues See more
    Orthologs
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    Genomic context

    See Ttc33 in Genome Data Viewer
    Location:
    15 A1; 15 1.99 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (5214971..5247817)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (5185490..5218336)

    Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 41256 Neighboring gene STARR-seq mESC enhancer starr_37844 Neighboring gene protein kinase, AMP-activated, alpha 1 catalytic subunit Neighboring gene predicted gene 15938 Neighboring gene heat shock protein 90, alpha (cytosolic), class A member 1 pseudogene Neighboring gene STARR-positive B cell enhancer ABC_E2436 Neighboring gene prostaglandin E receptor 4 (subtype EP4) Neighboring gene STARR-seq mESC enhancer starr_37846 Neighboring gene predicted gene, 41257 Neighboring gene ribosomal protein L22 like 1 pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (3) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
     
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
     

    General protein information

    Preferred Names
    tetratricopeptide repeat protein 33
    Names
    TPR repeat protein 33
    osmosis responsive factor

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001355620.1NP_001342549.1  tetratricopeptide repeat protein 33

      Status: VALIDATED

      Source sequence(s)
      AC135079
      Consensus CDS
      CCDS27364.1
      UniProtKB/Swiss-Prot
      Q8VIG5, Q9D6K7
      Related
      ENSMUSP00000114033.2, ENSMUST00000118193.8
      Conserved Domains (2) summary
      COG4783
      Location:42164
      YfgC; Putative Zn-dependent protease, contains TPR repeats [General function prediction only]
      sd00006
      Location:5987
      TPR; TPR repeat [structural motif]
    2. NM_001355621.1NP_001342550.1  tetratricopeptide repeat protein 33

      Status: VALIDATED

      Source sequence(s)
      AC135079
      Consensus CDS
      CCDS27364.1
      UniProtKB/Swiss-Prot
      Q8VIG5, Q9D6K7
      Conserved Domains (2) summary
      COG4783
      Location:42164
      YfgC; Putative Zn-dependent protease, contains TPR repeats [General function prediction only]
      sd00006
      Location:5987
      TPR; TPR repeat [structural motif]
    3. NM_026213.3NP_080489.1  tetratricopeptide repeat protein 33

      Status: VALIDATED

      Source sequence(s)
      AC135079
      Consensus CDS
      CCDS27364.1
      UniProtKB/Swiss-Prot
      Q8VIG5, Q9D6K7
      Related
      ENSMUSP00000022751.9, ENSMUST00000022751.15
      Conserved Domains (2) summary
      COG4783
      Location:42164
      YfgC; Putative Zn-dependent protease, contains TPR repeats [General function prediction only]
      sd00006
      Location:5987
      TPR; TPR repeat [structural motif]

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000081.7 Reference GRCm39 C57BL/6J

      Range
      5214971..5247817
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030248716.1XP_030104576.1  tetratricopeptide repeat protein 33 isoform X1

      UniProtKB/Swiss-Prot
      Q8VIG5, Q9D6K7
      Conserved Domains (2) summary
      COG4783
      Location:42164
      YfgC; Putative Zn-dependent protease, contains TPR repeats [General function prediction only]
      sd00006
      Location:5987
      TPR; TPR repeat [structural motif]