slc40a1.S solute carrier family 40 (iron-regulated transporter), member 1 S homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: slc40a1.S
Official Full Name: solute carrier family 40 (iron-regulated transporter), member 1 S homeolog
Primary source: Xenbase:XB-GENE-6078185
Locus tag: XELAEV_18047408mg
See related: EnsemblRapid:ENSXLAG00005015177 AllianceGenome:Xenbase:XB-GENE-6078185
Gene type: protein coding
RefSeq status: MODEL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: fpn1; mtp1; IREG1; slc11a3; slc39a1; slc40a1
Summary: Predicted to enable iron ion transmembrane transporter activity and metal ion binding activity. Predicted to act upstream of or within iron ion transmembrane transport. Predicted to be located in basolateral plasma membrane. Human ortholog(s) of this gene implicated in hemochromatosis type 4. Orthologous to human SLC40A1 (solute carrier family 40 member 1). [provided by Alliance of Genome Resources, Dec 2024]
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Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	9_10S	NC_054388.1 (82213415..82229157, complement)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	9_10S	NC_030741.1 (75515096..75532485, complement)

Chromosome 9_10S - NC_054388.1 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Submit: New GeneRIF Correction

Function	Evidence Code	Pubs
enables iron ion transmembrane transporter activity	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within iron ion transmembrane transport	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within monoatomic ion transport	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within transmembrane transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in basolateral plasma membrane	IEA Inferred from Electronic Annotation more info
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in plasma membrane	IEA Inferred from Electronic Annotation more info

Preferred Names: solute carrier family 40 (iron-regulated transporter), member 1 S homeolog; solute carrier family 40 member 1

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The following sections contain reference sequences that belong to a specific genome build. Explain

The following Reference Sequences have been suppressed. Explain

NM_001093357.1: Suppressed sequence

Description

NM_001093357.1: This RefSeq was removed because it is a nonsense-mediated mRNA decay (NMD) candidate.