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    pnhd.L pinhead L homeolog [ Xenopus laevis (African clawed frog) ]

    Gene ID: 100158295, updated on 4-Jan-2025

    Summary

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    Official Symbol
    pnhd.L
    Official Full Name
    pinhead L homeolog
    Primary source
    Xenbase:XB-GENE-6488002
    Locus tag
    XELAEV_18006391mg
    See related
    EnsemblRapid:ENSXLAG00005024233 AllianceGenome:Xenbase:XB-GENE-6488002
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Xenopus laevis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
    Also known as
    pnhd
    Summary
    Acts upstream of or within with a positive effect on fibroblast growth factor receptor signaling pathway. Acts upstream of or within with a negative effect on protein phosphorylation. Acts upstream of or within head development and mesodermal cell fate specification. Is active in extracellular space. Is expressed in ectoderm; endoderm; mesoderm; and nervous system. [provided by Alliance of Genome Resources, Jan 2025]
    Annotation information
    Annotation category: partial on reference assembly
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    Genomic context

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    See pnhd.L in Genome Data Viewer
    Location:
    chromosome: 1L
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 1L NC_054371.1 (114014032..114020542)
    100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 1L NC_030724.1 (101958834..101965344)

    Chromosome 1L - NC_054371.1Genomic Context describing neighboring genes Neighboring gene tropomyosin 4 L homeolog Neighboring gene RAB8A, member RAS oncogene family L homeolog Neighboring gene anti-dorsalizing morphogenic protein L homeolog Neighboring gene provisional ortholog of tetraspanin 3 L homeolog

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Pinhead signaling regulates mesoderm heterogeneity via the FGF receptor-dependent pathway. Ossipova O, et al. Development, 2020 Sep 11. PMID 32859582, Free PMC Article
    2. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by Xenbase

    Process Evidence Code Pubs
    acts_upstream_of_or_within_positive_effect fibroblast growth factor receptor signaling pathway IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within head development IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within head development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within mesoderm development IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in mesoderm development IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within mesodermal cell fate specification IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in mesodermal cell fate specification IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within_negative_effect protein phosphorylation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in extracellular space IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    pinhead L homeolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001127751.1 → NP_001121223.1  pinhead L homeolog precursor

      See identical proteins and their annotated locations for NP_001121223.1

      Status: PROVISIONAL

      Source sequence(s)
      BC160724
      UniProtKB/TrEMBL
      A0A974DZI2, B1H1S8
      Related
      ENSXLAP00005071783.1, ENSXLAT00005073329.1

    RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Xenopus_laevis_v10.1 Primary Assembly

    Genomic

    1. NC_054371.1 Reference Xenopus_laevis_v10.1 Primary Assembly

      Range
      114014032..114020542
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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