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    fabp2.L fatty acid binding protein 2 L homeolog [ Xenopus laevis (African clawed frog) ]

    Gene ID: 378690, updated on 9-Dec-2024

    Summary

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    Official Symbol
    fabp2.L
    Official Full Name
    fatty acid binding protein 2 L homeolog
    Primary source
    Xenbase:XB-GENE-864901
    Locus tag
    XELAEV_18005684mg
    See related
    AllianceGenome:Xenbase:XB-GENE-864901
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Xenopus laevis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
    Also known as
    IFABP; fabp2; fabp2a; fabp2-a; fabp2-b
    Summary
    Predicted to enable long-chain fatty acid binding activity. Predicted to act upstream of or within fatty acid transport. Predicted to be located in cytosol and nucleus. Is expressed in endoderm. Human ortholog(s) of this gene implicated in alcoholic liver cirrhosis; carotid stenosis; coronary artery disease; end stage renal disease; and obesity. Orthologous to human FABP2 (fatty acid binding protein 2). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See fabp2.L in Genome Data Viewer
    Location:
    chromosome: 1L
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 1L NC_054371.1 (75032972..75036196)
    100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 1L NC_030724.1 (64156266..64159492)

    Chromosome 1L - NC_054371.1Genomic Context describing neighboring genes Neighboring gene retinitis pigmentosa 1-like 1 protein Neighboring gene allregulin L homeolog Neighboring gene phosphodiesterase 5A L homeolog Neighboring gene mitotic arrest deficient 2 like 1 L homeolog

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Thyroid hormone-dependent regulation of the intestinal fatty acid-binding protein gene during amphibian metamorphosis. Shi YB, et al. Dev Biol, 1994 Jan. PMID 8293885
    2. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by Xenbase

    Function Evidence Code Pubs
    enables fatty acid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables lipid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    fatty acid-binding protein, intestinal
    Names
    FABPI
    I-FABP
    fatty acid binding protein 2, intestinal L homeolog
    fatty acid binding protein 2, intestinal a
    fatty acid-binding protein 2
    fatty acid-binding protein, intestinal a
    intestinal-type fatty acid-binding protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001085877.1 → NP_001079346.1  fatty acid-binding protein, intestinal

      See identical proteins and their annotated locations for NP_001079346.1

      Status: PROVISIONAL

      Source sequence(s)
      L19946
      UniProtKB/Swiss-Prot
      Q91775
      UniProtKB/TrEMBL
      A0A974DTH9, A0A974DYH9, B7ZQJ2
      Conserved Domains (1) summary
      cl21528
      Location:3 → 131
      Lipocalin; Lipocalin / cytosolic fatty-acid binding protein family

    RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Xenopus_laevis_v10.1 Primary Assembly

    Genomic

    1. NC_054371.1 Reference Xenopus_laevis_v10.1 Primary Assembly

      Range
      75032972..75036196
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q91775.2 GenPept UniProtKB/Swiss-Prot:Q91775

    Gene LinkOut

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