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    ventx2.S VENT homeobox 2 gene 1 S homeolog [ Xenopus laevis (African clawed frog) ]

    Gene ID: 397844, updated on 4-Jan-2025

    Summary

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    Official Symbol
    ventx2.S
    Official Full Name
    VENT homeobox 2 gene 1 S homeolog
    Primary source
    Xenbase:XB-GENE-6252342
    Locus tag
    XELAEV_18036903mg
    See related
    EnsemblRapid:ENSXLAG00005012746 AllianceGenome:Xenbase:XB-GENE-6252342
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Xenopus laevis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
    Also known as
    vox; xom; vox1; Xbr-1a; xbr-1b; Xvr-11b; xvent-2; ventx2.1; xvent-2b; ventx2.1-a; ventx2.1-b; ventx2.1.S
    Summary
    Predicted to enable DNA binding activity and DNA-binding transcription factor activity, RNA polymerase II-specific. Predicted to act upstream of or within regulation of DNA-templated transcription and spinal cord motor neuron cell fate specification. Predicted to be located in nucleus. Is expressed in ectoderm; nervous system; pharyngeal arch; and respiratory system. [provided by Alliance of Genome Resources, Jan 2025]
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    Genomic context

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    See ventx2.S in Genome Data Viewer
    Location:
    chromosome: 7S
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 7S NC_054384.1 (16926730..16928499, complement)
    100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 7S NC_030737.1 (16932132..16933901, complement)

    Chromosome 7S - NC_054384.1Genomic Context describing neighboring genes Neighboring gene VENT homeobox 2, gene 2 S homeolog Neighboring gene VENT homeobox 1 gene 1 S homeolog Neighboring gene adhesion G protein-coupled receptor A1 S homeolog Neighboring gene vertebrate ancient opsin S homeolog

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Regulation of dorsal-ventral patterning: the ventralizing effects of the novel Xenopus homeobox gene Vox. Schmidt JE, et al. Development, 1996 Jun. PMID 8674411
    2. A Xenopus gene, Xbr-1, defines a novel class of homeobox genes and is expressed in the dorsal ciliary margin of the eye. Papalopulu N, et al. Dev Biol, 1996 Feb 25. PMID 8626010
    3. The essential mitotic peptidyl-prolyl isomerase Pin1 binds and regulates mitosis-specific phosphoproteins. Shen M, et al. Genes Dev, 1998 Mar 1. PMID 9499405, Free PMC Article
    4. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by Xenbase

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within spinal cord motor neuron cell fate specification IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    VENT homeobox 2 gene 1 S homeolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001087981.1 → NP_001081450.1  VENT homeobox 2 gene 1 S homeolog

      See identical proteins and their annotated locations for NP_001081450.1

      Status: PROVISIONAL

      Source sequence(s)
      U43938
      UniProtKB/TrEMBL
      Q91669, Q91877
      Related
      ENSXLAP00005037478.1, ENSXLAT00005038387.1
      Conserved Domains (1) summary
      pfam00046
      Location:187 → 239
      Homeobox; Homeobox domain

    RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Xenopus_laevis_v10.1 Primary Assembly

    Genomic

    1. NC_054384.1 Reference Xenopus_laevis_v10.1 Primary Assembly

      Range
      16926730..16928499 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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