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    cyb5r2.S cytochrome b5 reductase 2 S homeolog [ Xenopus laevis (African clawed frog) ]

    Gene ID: 495932, updated on 27-Dec-2024

    Summary

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    Official Symbol
    cyb5r2.S
    Official Full Name
    cytochrome b5 reductase 2 S homeolog
    Primary source
    Xenbase:XB-GENE-1006047
    Locus tag
    XELAEV_18024424mg
    See related
    EnsemblRapid:ENSXLAG00005019687 AllianceGenome:Xenbase:XB-GENE-1006047
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Xenopus laevis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
    Also known as
    cyb5r2
    Summary
    Predicted to enable cytochrome-b5 reductase activity, acting on NAD(P)H. Predicted to act upstream of or within sterol biosynthetic process. Predicted to be located in membrane. Orthologous to human CYB5R2 (cytochrome b5 reductase 2). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See cyb5r2.S in Genome Data Viewer
    Location:
    chromosome: 4S
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 4S NC_054378.1 (11578272..11588421, complement)
    100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 4S NC_030731.1 (11426019..11436504, complement)

    Chromosome 4S - NC_054378.1Genomic Context describing neighboring genes Neighboring gene synaptotagmin 9 S homeolog Neighboring gene PTPRF interacting protein, binding protein 2 (liprin beta 2) S homeolog Neighboring gene traf2 and NCK-interacting protein kinase-like Neighboring gene uncharacterized LOC121393171

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by Xenbase

    Function Evidence Code Pubs
    enables cytochrome-b5 reductase activity, acting on NAD(P)H IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within sterol biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    NADH-cytochrome b5 reductase 2
    Names
    b5R.2
    NP_001088670.1
    XP_018115186.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001095201.1 → NP_001088670.1  NADH-cytochrome b5 reductase 2

      See identical proteins and their annotated locations for NP_001088670.1

      Status: PROVISIONAL

      Source sequence(s)
      BC087294
      UniProtKB/Swiss-Prot
      Q5PQA4
      UniProtKB/TrEMBL
      A0A974HKW8
      Related
      ENSXLAP00005057809.1, ENSXLAT00005059163.1
      Conserved Domains (2) summary
      cd06183
      Location:40 → 296
      cyt_b5_reduct_like; Cytochrome b5 reductase catalyzes the reduction of 2 molecules of cytochrome b5 using NADH as an electron donor. Like ferredoxin reductases, these proteins have an N-terminal FAD binding subdomain and a C-terminal NADH binding subdomain, separated by a ...
      PTZ00319
      Location:1 → 288
      PTZ00319; NADH-cytochrome B5 reductase; Provisional

    RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Xenopus_laevis_v10.1 Primary Assembly

    Genomic

    1. NC_054378.1 Reference Xenopus_laevis_v10.1 Primary Assembly

      Range
      11578272..11588421 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_018259697.2 → XP_018115186.1  NADH-cytochrome b5 reductase 2 isoform X1

      UniProtKB/TrEMBL
      A0A8J0V3Y4, A0A974HKW8
      Related
      ENSXLAP00005057815.1, ENSXLAT00005059169.1
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5PQA4.1 GenPept UniProtKB/Swiss-Prot:Q5PQA4

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.