krt12.5.S keratin 12, gene 5 S homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: krt12.5.S
Official Full Name: keratin 12, gene 5 S homeolog
Primary source: Xenbase:XB-GENE-1219328
Locus tag: XELAEV_18045889mg
See related: EnsemblRapid:ENSXLAG00005025781 AllianceGenome:Xenbase:XB-GENE-1219328
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: krt12; xk81b2; krt12.1; krt12.L; krt12.S
Summary: Predicted to enable structural molecule activity. Predicted to be located in intermediate filament. Is expressed in appendage; dermal system; and ectoderm. Human ortholog(s) of this gene implicated in Meesmann corneal dystrophy 1 and corneal dystrophy. Orthologous to human KRT12 (keratin 12). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

Location:: chromosome: 9_10S

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	9_10S	NC_054388.1 (1175573..1179217)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	9_10S	NC_030741.1 (1087207..1090663)

Chromosome 9_10S - NC_054388.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables structural molecule activity	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in intermediate filament	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: keratin, type I cytoskeletal 47 kDa

Names: B2 keratin; keratin 12 S homeolog; keratin 12, type I L homeolog; keratin 12, type I S homeolog; larval keratin

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001088963.1 → NP_001082432.1 keratin, type I cytoskeletal 47 kDa

See identical proteins and their annotated locations for NP_001082432.1

Status: PROVISIONAL

Source sequence(s)

BC097543

UniProtKB/TrEMBL

A0A974BSJ7, Q4QR57, Q7ZY83

Related

ENSXLAP00005076637.1, ENSXLAT00005078230.1

Conserved Domains (1) summary

pfam00038
Location:81 → 393

Filament; Intermediate filament protein

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

NC_054388.1 Reference Xenopus_laevis_v10.1 Primary Assembly

Range

1175573..1179217

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_041577700.1 → XP_041433634.1 keratin, type I cytoskeletal 47 kDa isoform X1

UniProtKB/TrEMBL

A0A8J1LW86, Q7ZY83

Conserved Domains (1) summary

pfam00038
Location:81 → 393

Filament; Intermediate filament protein