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    Taar1 trace amine-associated receptor 1 [ Mus musculus (house mouse) ]

    Gene ID: 111174, updated on 9-Dec-2024

    Summary

    Official Symbol
    Taar1provided by MGI
    Official Full Name
    trace amine-associated receptor 1provided by MGI
    Primary source
    MGI:MGI:2148258
    See related
    Ensembl:ENSMUSG00000056379 AllianceGenome:MGI:2148258
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Tar1; Trar1; taR-1
    Summary
    Enables trace-amine receptor activity. Involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway; and phospholipase C-activating G protein-coupled receptor signaling pathway. Acts upstream of or within G protein-coupled receptor signaling pathway. Is active in plasma membrane. Used to study schizophrenia. Orthologous to human TAAR1 (trace amine associated receptor 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    NEW
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    Genomic context

    See Taar1 in Genome Data Viewer
    Location:
    10 A4; 10 11.39 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (23796304..23797302)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (23920406..23921404)

    Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_26053 Neighboring gene vanin 3 Neighboring gene STARR-seq mESC enhancer starr_26055 Neighboring gene vanin 1 Neighboring gene STARR-seq mESC enhancer starr_26056 Neighboring gene trace amine-associated receptor 2 Neighboring gene trace amine-associated receptor 3

    Genomic regions, transcripts, and products

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables G protein-coupled amine receptor activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables G protein-coupled receptor activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables trace-amine receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables trace-amine receptor activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables trace-amine receptor activity ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane IC
    Inferred by Curator
    more info
    PubMed 
    located_in membrane RCA
    inferred from Reviewed Computational Analysis
    more info
    PubMed 
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    trace amine-associated receptor 1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_053205.1NP_444435.1  trace amine-associated receptor 1

      See identical proteins and their annotated locations for NP_444435.1

      Status: PROVISIONAL

      Source sequence(s)
      AF380187
      Consensus CDS
      CCDS23735.1
      UniProtKB/Swiss-Prot
      Q05A85, Q923Y8
      Related
      ENSMUSP00000049527.5, ENSMUST00000051532.5
      Conserved Domains (2) summary
      pfam00001
      Location:39301
      7tm_1; 7 transmembrane receptor (rhodopsin family)
      cl21561
      Location:37316
      7tm_4; Olfactory receptor

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000076.7 Reference GRCm39 C57BL/6J

      Range
      23796304..23797302
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)