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    Taar4 trace amine-associated receptor 4 [ Mus musculus (house mouse) ]

    Gene ID: 209513, updated on 27-Nov-2024

    Summary

    Official Symbol
    Taar4provided by MGI
    Official Full Name
    trace amine-associated receptor 4provided by MGI
    Primary source
    MGI:MGI:2685072
    See related
    Ensembl:ENSMUSG00000069707 AllianceGenome:MGI:2685072
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Ta2; Gm226; taR-4
    Summary
    Enables 2-phenylethylamine receptor activity and trace-amine receptor activity. Involved in behavioral fear response; chemosensory behavior; and sensory perception of chemical stimulus. Predicted to be active in plasma membrane. Is expressed in Grueneberg ganglion; nasal septum; and olfactory epithelium. Orthologous to human TAAR4P (trace amine associated receptor 4, pseudogene). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
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    Genomic context

    See Taar4 in Genome Data Viewer
    Location:
    10 A4; 10 11.4 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (23836392..23837435)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (23960494..23961537)

    Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene trace amine-associated receptor 2 Neighboring gene trace amine-associated receptor 3 Neighboring gene trace amine-associated receptor 5 Neighboring gene trace amine-associated receptor 6

    Genomic regions, transcripts, and products

    Bibliography

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 
    • Targeted (4)  1 citation

    Pathways from PubChem

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables 2-phenylethylamine receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables 2-phenylethylamine receptor activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables 2-phenylethylamine receptor activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    enables G protein-coupled amine receptor activity ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    enables trace-amine receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables trace-amine receptor activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables trace-amine receptor activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    enables trace-amine receptor activity ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in G protein-coupled receptor signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within G protein-coupled receptor signaling pathway RCA
    inferred from Reviewed Computational Analysis
    more info
    PubMed 
    involved_in behavioral fear response IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in behavioral fear response IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in chemosensory behavior IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in chemosensory behavior IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in sensory perception of chemical stimulus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in sensory perception of chemical stimulus IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    trace amine-associated receptor 4
    Names
    2-phenylethylamine receptor
    mTaar4
    trace amine receptor 2
    trace amine receptor 4

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001008499.1NP_001008499.1  trace amine-associated receptor 4

      See identical proteins and their annotated locations for NP_001008499.1

      Status: PROVISIONAL

      Source sequence(s)
      AY702328
      Consensus CDS
      CCDS23737.1
      UniProtKB/Swiss-Prot
      Q5QD15
      UniProtKB/TrEMBL
      A4FUU0
      Related
      ENSMUSP00000090330.2, ENSMUST00000092660.2
      Conserved Domains (2) summary
      pfam00001
      Location:50313
      7tm_1; 7 transmembrane receptor (rhodopsin family)
      cl21561
      Location:34170
      7tm_4; Olfactory receptor

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000076.7 Reference GRCm39 C57BL/6J

      Range
      23836392..23837435
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)