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    4921539E11Rik RIKEN cDNA 4921539E11 gene [ Mus musculus (house mouse) ]

    Gene ID: 70941, updated on 27-Nov-2024

    Summary

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    Official Symbol
    4921539E11Rikprovided by MGI
    Official Full Name
    RIKEN cDNA 4921539E11 geneprovided by MGI
    Primary source
    MGI:MGI:1918191
    See related
    Ensembl:ENSMUSG00000028520 AllianceGenome:MGI:1918191
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Summary
    Orthologous to human C1orf141 (chromosome 1 open reading frame 141). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Restricted expression toward testis adult (RPKM 9.9) See more
    Orthologs
    human all
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    Genomic context

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    See 4921539E11Rik in Genome Data Viewer
    Location:
    4 C6; 4 47.5 cM
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (103087642..103148141, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (103230445..103290954, complement)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene dynein axonemal intermediate chain 4 Neighboring gene MEIR1 treanscription regulator Neighboring gene STARR-seq mESC enhancer starr_10936 Neighboring gene solute carrier family 35 (UDP-glucuronic acid/UDP-N-acetylgalactosamine dual transporter), member D1 Neighboring gene STARR-seq mESC enhancer starr_10938 Neighboring gene STARR-seq mESC enhancer starr_10939 Neighboring gene RIKEN cDNA 4930456L15 gene Neighboring gene CapStarr-seq enhancer MGSCv37_chr4:102986166-102986353 Neighboring gene predicted gene, 36523 Neighboring gene OMA1 zinc metallopeptidase

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. CRISPR/Cas9-mediated genome editing reveals 12 testis-enriched genes dispensable for male fertility in mice. Oyama Y, et al. Asian J Androl, 2022 May-Jun. PMID 34290169, Free PMC Article
    2. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    3. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
    4. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article
    5. Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. Carninci P, et al. Genome Res, 2000 Oct. PMID 11042159, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    General gene information

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    Homology

    Clone Names

    • MGC130412, MGC130413

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein C1orf141 homolog

    NCBI Reference Sequences (RefSeq)

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    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001163494.1 → NP_001156966.1  uncharacterized protein C1orf141 homolog isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR, lacks an alternate exon in the 5' coding region and uses a downstream start codon, compared to variant 1. The resulting isoform (2) has a shorter N-terminus compared to isoform 1.
      Source sequence(s)
      AL772338
      Consensus CDS
      CCDS51247.1
      UniProtKB/Swiss-Prot
      Q9D5Q8
      Related
      ENSMUSP00000131846.2, ENSMUST00000168664.8
      Conserved Domains (1) summary
      pfam15078
      Location:1 → 342
      DUF4545; Domain of unknown function (DUF4545)

    2. NM_027612.1 → NP_081888.1  uncharacterized protein C1orf141 homolog isoform 1

      See identical proteins and their annotated locations for NP_081888.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
      Source sequence(s)
      AK015018, BB615869, BX631077
      Consensus CDS
      CCDS51248.1
      UniProtKB/Swiss-Prot
      A2AKQ4, Q3KN93, Q3KN94, Q3TTD9, Q9D5Q8
      Related
      ENSMUSP00000030245.4, ENSMUST00000030245.10
      Conserved Domains (1) summary
      pfam15078
      Location:1 → 443
      DUF4545; Domain of unknown function (DUF4545)

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      103087642..103148141 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006503396.4 → XP_006503459.1  uncharacterized protein C1orf141 homolog isoform X3

      See identical proteins and their annotated locations for XP_006503459.1

      Conserved Domains (1) summary
      pfam15078
      Location:22 → 251
      DUF4545; Domain of unknown function (DUF4545)

    2. XM_006503395.3 → XP_006503458.1  uncharacterized protein C1orf141 homolog isoform X1

      Conserved Domains (1) summary
      pfam15078
      Location:1 → 431
      DUF4545; Domain of unknown function (DUF4545)

    3. XM_006503397.1 → XP_006503460.1  uncharacterized protein C1orf141 homolog isoform X3

      See identical proteins and their annotated locations for XP_006503460.1

      Conserved Domains (1) summary
      pfam15078
      Location:22 → 251
      DUF4545; Domain of unknown function (DUF4545)

    4. XM_017320385.3 → XP_017175874.1  uncharacterized protein C1orf141 homolog isoform X2

      Related
      ENSMUSP00000095557.4, ENSMUST00000097944.4
      Conserved Domains (1) summary
      pfam15078
      Location:1 → 265
      DUF4545; Domain of unknown function (DUF4545)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9D5Q8.1 GenPept UniProtKB/Swiss-Prot:Q9D5Q8

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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