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    Paqr3 progestin and adipoQ receptor family member III [ Mus musculus (house mouse) ]

    Gene ID: 231474, updated on 3-Dec-2024

    Summary

    Official Symbol
    Paqr3provided by MGI
    Official Full Name
    progestin and adipoQ receptor family member IIIprovided by MGI
    Primary source
    MGI:MGI:2679683
    See related
    Ensembl:ENSMUSG00000055725 AllianceGenome:MGI:2679683
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    RKTG; 6330415A20Rik
    Summary
    Predicted to enable signaling receptor activity. Acts upstream of or within negative regulation of MAP kinase activity. Predicted to be located in Golgi apparatus. Is expressed in cerebral cortex intermediate zone and cortical plate. Orthologous to human PAQR3 (progestin and adipoQ receptor family member 3). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Ubiquitous expression in ovary adult (RPKM 5.7), whole brain E14.5 (RPKM 5.6) and 28 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Paqr3 in Genome Data Viewer
    Location:
    5 E3; 5 47.29 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (97229223..97259608, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (97081364..97111749, complement)

    Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 46916 Neighboring gene STARR-positive B cell enhancer ABC_E11294 Neighboring gene STARR-seq mESC enhancer starr_13683 Neighboring gene STARR-positive B cell enhancer ABC_E1303 Neighboring gene CapStarr-seq enhancer MGSCv37_chr5:97425959-97426223 Neighboring gene predicted gene 9484 Neighboring gene BMP2 inducible kinase Neighboring gene STARR-positive B cell enhancer ABC_E3589 Neighboring gene STARR-seq mESC enhancer starr_13685 Neighboring gene STARR-seq mESC enhancer starr_13686 Neighboring gene STARR-positive B cell enhancer mm9_chr5:97540551-97540852 Neighboring gene predicted gene, 33609 Neighboring gene STARR-seq mESC enhancer starr_13687 Neighboring gene predicted gene 2861

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables ubiquitin-like ligase-substrate adaptor activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in Golgi apparatus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    located_in Golgi membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    progestin and adipoQ receptor family member 3
    Names
    Raf kinase trapping to Golgi

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001359910.2NP_001346839.1  progestin and adipoQ receptor family member 3 isoform a

      Status: VALIDATED

      Source sequence(s)
      AC125229
      Consensus CDS
      CCDS19451.1
      UniProtKB/Swiss-Prot
      Q6TCG8
      UniProtKB/TrEMBL
      Q0VAZ2, Q3UEZ4
      Related
      ENSMUSP00000108593.4, ENSMUST00000112969.10
      Conserved Domains (1) summary
      pfam03006
      Location:64283
      HlyIII; Haemolysin-III related
    2. NM_001359913.2NP_001346842.1  progestin and adipoQ receptor family member 3 isoform b

      Status: VALIDATED

      Source sequence(s)
      AC125229
      Consensus CDS
      CCDS89954.1
      UniProtKB/TrEMBL
      D3Z181
      Related
      ENSMUSP00000108592.2, ENSMUST00000112968.2
      Conserved Domains (1) summary
      cl03831
      Location:64170
      HlyIII; Haemolysin-III related
    3. NM_001428771.1NP_001415700.1  progestin and adipoQ receptor family member 3 isoform a

      Status: VALIDATED

      Source sequence(s)
      AC125229
      UniProtKB/Swiss-Prot
      Q6TCG8
      UniProtKB/TrEMBL
      Q0VAZ2, Q3UEZ4
    4. NM_001428772.1NP_001415701.1  progestin and adipoQ receptor family member 3 isoform a

      Status: VALIDATED

      Source sequence(s)
      AC125229
      UniProtKB/Swiss-Prot
      Q6TCG8
      UniProtKB/TrEMBL
      Q0VAZ2, Q3UEZ4
    5. NM_001428773.1NP_001415702.1  progestin and adipoQ receptor family member 3 isoform c

      Status: VALIDATED

      Source sequence(s)
      AC125229
      UniProtKB/TrEMBL
      Q3UEZ4
    6. NM_001428774.1NP_001415703.1  progestin and adipoQ receptor family member 3 isoform c

      Status: VALIDATED

      Source sequence(s)
      AC125229
      UniProtKB/TrEMBL
      Q3UEZ4
    7. NM_001428775.1NP_001415704.1  progestin and adipoQ receptor family member 3 isoform d

      Status: VALIDATED

      Source sequence(s)
      AC125229
    8. NM_001428776.1NP_001415705.1  progestin and adipoQ receptor family member 3 isoform d

      Status: VALIDATED

      Source sequence(s)
      AC125229
    9. NM_198422.4NP_940814.1  progestin and adipoQ receptor family member 3 isoform a

      See identical proteins and their annotated locations for NP_940814.1

      Status: VALIDATED

      Source sequence(s)
      AC125229
      Consensus CDS
      CCDS19451.1
      UniProtKB/Swiss-Prot
      Q6TCG8
      UniProtKB/TrEMBL
      Q0VAZ2, Q3UEZ4
      Related
      ENSMUSP00000069324.3, ENSMUST00000069453.9
      Conserved Domains (1) summary
      pfam03006
      Location:64283
      HlyIII; Haemolysin-III related

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000071.7 Reference GRCm39 C57BL/6J

      Range
      97229223..97259608 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036165068.1XP_036020961.1  progestin and adipoQ receptor family member 3 isoform X3

      Conserved Domains (1) summary
      cl03831
      Location:64217
      HlyIII; Haemolysin-III related
    2. XM_006534876.4XP_006534939.1  progestin and adipoQ receptor family member 3 isoform X2

      Conserved Domains (1) summary
      cl03831
      Location:64262
      HlyIII; Haemolysin-III related
    3. XM_006534875.5XP_006534938.1  progestin and adipoQ receptor family member 3 isoform X1

      Conserved Domains (1) summary
      pfam03006
      Location:64283
      HlyIII; Haemolysin-III related
    4. XM_036165067.1XP_036020960.1  progestin and adipoQ receptor family member 3 isoform X2

      Conserved Domains (1) summary
      cl03831
      Location:64262
      HlyIII; Haemolysin-III related