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    Naa11 N(alpha)-acetyltransferase 11, NatA catalytic subunit [ Mus musculus (house mouse) ]

    Gene ID: 97243, updated on 9-Dec-2024

    Summary

    Official Symbol
    Naa11provided by MGI
    Official Full Name
    N(alpha)-acetyltransferase 11, NatA catalytic subunitprovided by MGI
    Primary source
    MGI:MGI:2141314
    See related
    Ensembl:ENSMUSG00000046000 AllianceGenome:MGI:2141314
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Ard2; Ard1b
    Summary
    Predicted to enable peptide-glutamate-alpha-N-acetyltransferase activity and peptide-serine-alpha-N-acetyltransferase activity. Predicted to be involved in N-terminal protein amino acid acetylation. Predicted to be located in several cellular components, including Golgi apparatus; centrosome; and nucleoplasm. Predicted to be part of NatA complex. Is expressed in embryo; metanephros; and testis. Orthologous to human NAA11 (N-alpha-acetyltransferase 11, NatA catalytic subunit). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Restricted expression toward testis adult (RPKM 4.4) See more
    Orthologs
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    Genomic context

    See Naa11 in Genome Data Viewer
    Location:
    5 E3; 5 47.62 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (97530068..97540189, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (97382209..97392330, complement)

    Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene solute carrier family 25 member 5 pseudogene Neighboring gene STARR-seq mESC enhancer starr_13692 Neighboring gene predicted gene, 33969 Neighboring gene STARR-positive B cell enhancer mm9_chr5:97791676-97791976 Neighboring gene RIKEN cDNA 4930467D21 gene Neighboring gene glycerol kinase 2 Neighboring gene STARR-seq mESC enhancer starr_13693 Neighboring gene predicted gene, 34029

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables peptide alpha-N-acetyltransferase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables peptide-alanine-alpha-N-acetyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables peptide-glutamate-alpha-N-acetyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables peptide-serine-alpha-N-acetyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables peptide-serine-alpha-N-acetyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in N-terminal protein amino acid acetylation ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
     
    part_of NatA complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of NatA complex IEA
    Inferred from Electronic Annotation
    more info
     
    part_of NatA complex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in centrosome ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    N-alpha-acetyltransferase 11
    Names
    ARD1 homolog B
    N-terminal acetyltransferase complex ARD1 subunit homolog B
    Nalpha acteyltransferase 11
    arrest defective 2
    natA catalytic subunit Naa11
    NP_001028363.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001033191.2NP_001028363.1  N-alpha-acetyltransferase 11

      See identical proteins and their annotated locations for NP_001028363.1

      Status: PROVISIONAL

      Source sequence(s)
      AK135863
      Consensus CDS
      CCDS19453.1
      UniProtKB/Swiss-Prot
      Q3UX61, Q3V0C7
      UniProtKB/TrEMBL
      A8W660
      Related
      ENSMUSP00000057336.5, ENSMUST00000060265.6
      Conserved Domains (2) summary
      COG0456
      Location:1149
      RimI; Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal structure and biogenesis]
      pfam00583
      Location:47122
      Acetyltransf_1; Acetyltransferase (GNAT) family

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000071.7 Reference GRCm39 C57BL/6J

      Range
      97530068..97540189 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)