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    Gk2 glycerol kinase 2 [ Mus musculus (house mouse) ]

    Gene ID: 14626, updated on 9-Dec-2024

    Summary

    Official Symbol
    Gk2provided by MGI
    Official Full Name
    glycerol kinase 2provided by MGI
    Primary source
    MGI:MGI:1329027
    See related
    Ensembl:ENSMUSG00000050553 AllianceGenome:MGI:1329027
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    GKTA; Gk-rs2
    Summary
    Predicted to enable glycerol kinase activity. Involved in sperm mitochondrial sheath assembly. Located in mitochondrial outer membrane and sperm mitochondrial sheath. Orthologous to human GK2 (glycerol kinase 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    NEW
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    Genomic context

    See Gk2 in Genome Data Viewer
    Location:
    5 E3; 5 47.71 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (97602989..97604882, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (97455130..97457023, complement)

    Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_13692 Neighboring gene predicted gene, 33969 Neighboring gene STARR-positive B cell enhancer mm9_chr5:97791676-97791976 Neighboring gene RIKEN cDNA 4930467D21 gene Neighboring gene N(alpha)-acetyltransferase 11, NatA catalytic subunit Neighboring gene STARR-seq mESC enhancer starr_13693 Neighboring gene predicted gene, 34029 Neighboring gene predicted gene, 54318

    Genomic regions, transcripts, and products

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables glycerol kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables glycerol kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in flagellated sperm motility IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in glycerol catabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in glycerol metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in glycerol-3-phosphate biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in glycerol-3-phosphate metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in sperm mitochondrial sheath assembly IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in spermatogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in triglyceride metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in mitochondrial outer membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in mitochondrion HDA PubMed 
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in sperm midpiece ISO
    Inferred from Sequence Orthology
    more info
     
    located_in sperm midpiece ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in sperm mitochondrial sheath IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    glycerol kinase 2
    Names
    ATP:glycerol 3-phosphotransferase 2
    GK 2
    glucokinase activity, related sequence 2
    glycerokinase 2
    glycerol kinase, testis specific 2
    NP_034424.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_010294.2NP_034424.1  glycerol kinase 2

      See identical proteins and their annotated locations for NP_034424.1

      Status: VALIDATED

      Source sequence(s)
      AC122875, BC050764, BC061147
      Consensus CDS
      CCDS19454.1
      UniProtKB/Swiss-Prot
      Q9WU65
      UniProtKB/TrEMBL
      Q8BW08
      Related
      ENSMUSP00000052226.3, ENSMUST00000059657.4
      Conserved Domains (2) summary
      cd07792
      Location:11513
      FGGY_GK1-3_metazoa; Metazoan glycerol kinase 1 and 3-like proteins; belongs to the FGGY family of carbohydrate kinases
      TIGR01311
      Location:11513
      glycerol_kin; glycerol kinase

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000071.7 Reference GRCm39 C57BL/6J

      Range
      97602989..97604882 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)