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    PPFIA1 PTPRF interacting protein alpha 1 [ Bos taurus (domestic cattle) ]

    Gene ID: 100139635, updated on 29-Jan-2025

    Summary

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    Official Symbol
    PPFIA1provided by VGNC
    Official Full Name
    PTPRF interacting protein alpha 1provided by VGNC
    Primary source
    VGNC:VGNC:56275
    See related
    BGD:BT11447; Ensembl:ENSBTAG00000022188
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See PPFIA1 in Genome Data Viewer
    Location:
    chromosome: 29
    Exon count:
    33
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 29 NC_037356.1 (47421119..47498037)

    Chromosome 29 - NC_037356.1Genomic Context describing neighboring genes Neighboring gene Fas associated via death domain Neighboring gene adenylosuccinate lyase-like Neighboring gene cortactin Neighboring gene uncharacterized LOC132344223

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037356.1 Chromosome 29 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in synapse organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in presynaptic active zone IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    liprin-alpha-1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001191377.3 → NP_001178306.1  liprin-alpha-1

      See identical proteins and their annotated locations for NP_001178306.1

      Status: PROVISIONAL

      Source sequence(s)
      NKLS02000029
      UniProtKB/TrEMBL
      F1MD37
      Related
      ENSBTAP00070044607.1, ENSBTAT00070073226.1
      Conserved Domains (4) summary
      cd09562
      Location:875 → 945
      SAM_liprin-alpha1,2,3,4_repeat1; SAM domain of liprin-alpha1,2,3,4 proteins repeat 1
      cd09565
      Location:962 → 1027
      SAM_liprin-alpha1,2,3,4_repeat2; SAM domain of liprin-alpha1,2,3,4 proteins repeat 2
      cd09568
      Location:1047 → 1118
      SAM_liprin-alpha1,2,3,4_repeat3; SAM domain of liprin-alpha1,2,3,4 proteins repeat 3
      cl25732
      Location:270 → 517
      SMC_N; RecF/RecN/SMC N terminal domain

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037356.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      47421119..47498037
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024986953.2 → XP_024842721.1  liprin-alpha-1 isoform X3

      UniProtKB/TrEMBL
      F1MD37
      Conserved Domains (4) summary
      cd09562
      Location:875 → 945
      SAM_liprin-alpha1,2,3,4_repeat1; SAM domain of liprin-alpha1,2,3,4 proteins repeat 1
      cd09565
      Location:992 → 1057
      SAM_liprin-alpha1,2,3,4_repeat2; SAM domain of liprin-alpha1,2,3,4 proteins repeat 2
      cd09568
      Location:1077 → 1148
      SAM_liprin-alpha1,2,3,4_repeat3; SAM domain of liprin-alpha1,2,3,4 proteins repeat 3
      cl25732
      Location:270 → 517
      SMC_N; RecF/RecN/SMC N terminal domain

    2. XM_024986954.2 → XP_024842722.1  liprin-alpha-1 isoform X4

      UniProtKB/TrEMBL
      F1MD37
      Conserved Domains (4) summary
      cd09562
      Location:875 → 945
      SAM_liprin-alpha1,2,3,4_repeat1; SAM domain of liprin-alpha1,2,3,4 proteins repeat 1
      cd09565
      Location:983 → 1048
      SAM_liprin-alpha1,2,3,4_repeat2; SAM domain of liprin-alpha1,2,3,4 proteins repeat 2
      cd09568
      Location:1068 → 1139
      SAM_liprin-alpha1,2,3,4_repeat3; SAM domain of liprin-alpha1,2,3,4 proteins repeat 3
      cl25732
      Location:270 → 517
      SMC_N; RecF/RecN/SMC N terminal domain

    3. XM_024986956.2 → XP_024842724.1  liprin-alpha-1 isoform X6

      UniProtKB/TrEMBL
      F1MD37
      Related
      ENSBTAP00070044579.1, ENSBTAT00070073182.1
      Conserved Domains (4) summary
      cd09562
      Location:875 → 945
      SAM_liprin-alpha1,2,3,4_repeat1; SAM domain of liprin-alpha1,2,3,4 proteins repeat 1
      cd09565
      Location:962 → 1027
      SAM_liprin-alpha1,2,3,4_repeat2; SAM domain of liprin-alpha1,2,3,4 proteins repeat 2
      cd09568
      Location:1047 → 1118
      SAM_liprin-alpha1,2,3,4_repeat3; SAM domain of liprin-alpha1,2,3,4 proteins repeat 3
      cl25732
      Location:270 → 517
      SMC_N; RecF/RecN/SMC N terminal domain

    4. XM_059882746.1 → XP_059738729.1  liprin-alpha-1 isoform X9

      UniProtKB/TrEMBL
      F1MD37

    5. XM_005227265.5 → XP_005227322.1  liprin-alpha-1 isoform X1

      UniProtKB/TrEMBL
      F1MD37
      Conserved Domains (6) summary
      cd09562
      Location:875 → 945
      SAM_liprin-alpha1,2,3,4_repeat1; SAM domain of liprin-alpha1,2,3,4 proteins repeat 1
      cd09565
      Location:992 → 1057
      SAM_liprin-alpha1,2,3,4_repeat2; SAM domain of liprin-alpha1,2,3,4 proteins repeat 2
      cd09568
      Location:1077 → 1148
      SAM_liprin-alpha1,2,3,4_repeat3; SAM domain of liprin-alpha1,2,3,4 proteins repeat 3
      smart00454
      Location:1078 → 1148
      SAM; Sterile alpha motif
      pfam12795
      Location:321 → 517
      MscS_porin; Mechanosensitive ion channel porin domain
      cl12013
      Location:324 → 445
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

    6. XM_024986952.2 → XP_024842720.1  liprin-alpha-1 isoform X2

      UniProtKB/TrEMBL
      E1BBK8, F1MD37
      Related
      ENSBTAP00070044639.1, ENSBTAT00070073271.1
      Conserved Domains (4) summary
      cd09562
      Location:875 → 945
      SAM_liprin-alpha1,2,3,4_repeat1; SAM domain of liprin-alpha1,2,3,4 proteins repeat 1
      cd09565
      Location:983 → 1048
      SAM_liprin-alpha1,2,3,4_repeat2; SAM domain of liprin-alpha1,2,3,4 proteins repeat 2
      cd09568
      Location:1068 → 1139
      SAM_liprin-alpha1,2,3,4_repeat3; SAM domain of liprin-alpha1,2,3,4 proteins repeat 3
      cl25732
      Location:270 → 517
      SMC_N; RecF/RecN/SMC N terminal domain

    7. XM_024986955.2 → XP_024842723.1  liprin-alpha-1 isoform X5

      UniProtKB/TrEMBL
      F1MD37
      Conserved Domains (4) summary
      cd09562
      Location:875 → 945
      SAM_liprin-alpha1,2,3,4_repeat1; SAM domain of liprin-alpha1,2,3,4 proteins repeat 1
      cd09565
      Location:962 → 1027
      SAM_liprin-alpha1,2,3,4_repeat2; SAM domain of liprin-alpha1,2,3,4 proteins repeat 2
      cd09568
      Location:1047 → 1118
      SAM_liprin-alpha1,2,3,4_repeat3; SAM domain of liprin-alpha1,2,3,4 proteins repeat 3
      cl25732
      Location:270 → 517
      SMC_N; RecF/RecN/SMC N terminal domain

    8. XM_024986957.2 → XP_024842725.1  liprin-alpha-1 isoform X8

      UniProtKB/TrEMBL
      A0A3Q1N164
      Conserved Domains (4) summary
      cd09562
      Location:735 → 805
      SAM_liprin-alpha1,2,3,4_repeat1; SAM domain of liprin-alpha1,2,3,4 proteins repeat 1
      cd09565
      Location:852 → 917
      SAM_liprin-alpha1,2,3,4_repeat2; SAM domain of liprin-alpha1,2,3,4 proteins repeat 2
      cd09568
      Location:937 → 1008
      SAM_liprin-alpha1,2,3,4_repeat3; SAM domain of liprin-alpha1,2,3,4 proteins repeat 3
      cl25732
      Location:31 → 375
      SMC_N; RecF/RecN/SMC N terminal domain

    9. XM_059882745.1 → XP_059738728.1  liprin-alpha-1 isoform X7

      UniProtKB/TrEMBL
      F1MD37
    Nucleotide Protein Strain
    Heading Accession and Version

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